ID W5PNN5_SHEEP Unreviewed; 718 AA.
AC W5PNN5;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=MACPF domain-containing protein {ECO:0000259|PROSITE:PS51412};
GN Name=LOC101110088 {ECO:0000313|Ensembl:ENSOARP00000012061.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000012061.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000012061.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000012061.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000012061.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01033649; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01033650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9940.ENSOARP00000012061; -.
DR PaxDb; 9940-ENSOARP00000012061; -.
DR Ensembl; ENSOART00000012237.1; ENSOARP00000012061.1; ENSOARG00000011258.1.
DR eggNOG; ENOG502QRKR; Eukaryota.
DR HOGENOM; CLU_023578_1_0_1; -.
DR OMA; YTAKLQP; -.
DR Proteomes; UP000002356; Chromosome 15.
DR Bgee; ENSOARG00000011258; Expressed in conceptus and 5 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd22579; MPEG1_P2; 1.
DR InterPro; IPR020864; MACPF.
DR InterPro; IPR039707; MPEG1.
DR PANTHER; PTHR31463; MACROPHAGE-EXPRESSED GENE 1 PROTEIN; 1.
DR PANTHER; PTHR31463:SF5; MACROPHAGE-EXPRESSED GENE 1 PROTEIN; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00457; MACPF; 1.
DR PROSITE; PS51412; MACPF_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..718
FT /note="MACPF domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004869163"
FT TRANSMEM 653..675
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..339
FT /note="MACPF"
FT /evidence="ECO:0000259|PROSITE:PS51412"
FT REGION 698..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 718 AA; 78290 MW; 4919EF8DF2BD48B6 CRC64;
LGRAPLLVLL WVGLGGRADE GPWGFQGCKQ QLNVSVLGAL PGAGWDNLRN MELGLVLGRA
YSQCLTTEDG EYLIPDGMLA VPRRESLVQT RADLMDSWVN YTDTWAASVN AEFSFLSFLN
GKFSVECQNV RRYSLQYQTI TTRVQRRHSI YSVRVRGTPD FHPDFRQRLL TLSDHLENNQ
TLEAEYLAEM LVFTYGTHVL TEVEVGATLV QEDQVSRELV GHEDRNRLNV TFAASALFAR
KIGVGDVVSW DKQRQLVQAY QQGTVASKIH SRGGPPFYEG LTLQKWQEGV ANRLVAIDRS
GLPLPALLQP EALPELPAPA VRRVEAAVSR AIGRYYAVNM HPGCVKXSPP RANVEVGWCT
DGQHANFSFG GVFQECEAIT GPEGGRLCAP YTILNPLTGR TSCPANYTAS PLSSEVKVWS
ERSYQCWPRC ERCWLIFTCC HRMCGFREVQ RVVRVNASWC APSGAAPTAA AGLLFGGLYS
PGRPNARTGA QACPSSFFPL TLLGDLKVCV SSDWELGAAH AVPFGGFFSC QVGNPLAARA
RGQDPESLKT CPEGYSQHPA YLSSGCQVQY CLRAGFLLNP QQLMVRLPPF VARPSLLGNS
SGLRASVLVD ASGQRAWVKL QGSSLWRQTD IHDPSVAAQL LDKGGSRPSA GTIASACLGA
VLGVIALALG VTWGFRRYQK RGYRRLPEGI LAEEQTVYGT AETAESPTPS GCSENANN
//
