ID W5PPV6_SHEEP Unreviewed; 824 AA.
AC W5PPV6; A0A6P3TTF4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Cell division cycle protein 27 homolog {ECO:0000256|ARBA:ARBA00039307};
GN Name=CDC27 {ECO:0000313|Ensembl:ENSOARP00000012483.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000012483.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000012483.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000012483.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000012483.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the APC3/CDC27 family.
CC {ECO:0000256|ARBA:ARBA00038210}.
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DR EMBL; AMGL01018839; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01018840; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01018841; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012041642.1; XM_012186252.2.
DR AlphaFoldDB; W5PPV6; -.
DR Ensembl; ENSOART00000012666.1; ENSOARP00000012483.1; ENSOARG00000011644.1.
DR GeneID; 101121276; -.
DR CTD; 996; -.
DR HOGENOM; CLU_008850_1_0_1; -.
DR OrthoDB; 152021at2759; -.
DR Proteomes; UP000002356; Chromosome 11.
DR Bgee; ENSOARG00000011644; Expressed in embryo and 54 other cell types or tissues.
DR ExpressionAtlas; W5PPV6; baseline and differential.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF13; CELL DIVISION CYCLE PROTEIN 27 HOMOLOG; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF00515; TPR_1; 2.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 5.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
SQ SEQUENCE 824 AA; 91741 MW; D7D0BD4C5F4CD6F8 CRC64;
MTVLQEPVQA AIWQALNHYA YRDAVFLAER LYAEVHSEEA LFLLATCYYR SGKAYKAYRL
LKGHSCTTPQ CKYLLAKCCV DLSKLAEGEQ ILSGGVFNKQ KSHDDIVTEF GDSACFTLSL
LGHVYCKTDR LAKGSECYQK SLSLNPFLWS PFESLCEIGE KPDPDQTFKL TSLQNFSSCL
PNSCTTLVSN HSLSHRQPET VLTETPQDTI ELNRLNLESS NSKYSLNTDS SVSYIDSAVI
SPDTVPLGTG TSILSKQVQN KPKTGRSLLG GPAALSPLTP SFGILPLETP SPGDGSYLQN
YTNTSSVIDV PPTGAPSKKS VARIGQTGTK SVFSQSGNSR EVTPILVAQT QSSGPQTSTT
PQVLSPTITS PPNALPRRSS RLFTSDSSTT KENSKKLKMK FPPKIPNRKT KSKTNKGGIT
QPNINDSLEI TKLDSSIISE GKISTITPQI QAFNLQKAAA GLMSLLREMG KGYLALCSYN
CKEAINILSH LPSHHYNTGW VLCQIGRAYF ELSEYMQAER IFSEVRRIEN YRVEGMEIYS
TTLWHLQKDV ALSVLSKDLT DMDKNSPEAW CAAGNCFSLQ REHDIAIKFF QRAIQVDPNY
AYAYTLLGHE FVLTEELDKA LACFRNAIRV NPRHYNAWYG LGMIYYKQEK FSLAEMHFQK
ALDINPQSSV LLCHIGVVQH ALKKSEKALD TLNKAIVIDP KNPLCKFHRA SVLFANEKYK
SALQELEELK QIVPKESLVY FLIGKVYKKL GQTHLALMNF SWAMDLDPKG ANNQIKEAID
KRYLPDDEEP ITQEEQIMGT DESQESSMTD ADDTQLHAAE SDEF
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