ID W5PQM6_SHEEP Unreviewed; 524 AA.
AC W5PQM6; A0A6P3TKJ8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Motile sperm domain-containing protein 2 {ECO:0008006|Google:ProtNLM};
GN Name=MOSPD2 {ECO:0000313|Ensembl:ENSOARP00000012753.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000012753.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000012753.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000012753.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000012753.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01113849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01113850; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01113851; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_011961631.1; XM_012106241.2.
DR AlphaFoldDB; W5PQM6; -.
DR SMR; W5PQM6; -.
DR STRING; 9940.ENSOARP00000012753; -.
DR PaxDb; 9940-ENSOARP00000012753; -.
DR Ensembl; ENSOART00000012940.1; ENSOARP00000012753.1; ENSOARG00000011895.1.
DR GeneID; 101122573; -.
DR CTD; 158747; -.
DR eggNOG; KOG0439; Eukaryota.
DR eggNOG; KOG1470; Eukaryota.
DR OMA; CHTVENS; -.
DR OrthoDB; 2168468at2759; -.
DR Proteomes; UP000002356; Chromosome X.
DR Bgee; ENSOARG00000011895; Expressed in spleen and 53 other cell types or tissues.
DR ExpressionAtlas; W5PQM6; baseline.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR GO; GO:0140284; C:endoplasmic reticulum-endosome membrane contact site; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0033149; F:FFAT motif binding; IEA:Ensembl.
DR GO; GO:0140042; P:lipid droplet formation; IEA:Ensembl.
DR GO; GO:0090026; P:positive regulation of monocyte chemotaxis; IEA:Ensembl.
DR GO; GO:0090023; P:positive regulation of neutrophil chemotaxis; IEA:Ensembl.
DR GO; GO:0051260; P:protein homooligomerization; IEA:Ensembl.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR46384; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR46384:SF1; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50202; MSP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
SQ SEQUENCE 524 AA; 60199 MW; 26203CBF9B89A6BE CRC64;
MSTTATIAEY QAQNKAKLIS EVRRRFEAEY VTDKSDKYDS RDVERLQQDD NWIESYLAWR
HNVVDETLKM LDESFQWRKE MAVNDLTEAS IPRWLLEIGG IYLHGYDKEG NKLFWIRVKY
HIKDHKTILD KKKLIAFWLE RYAKRENGKP VTVMFDLSET GLNSIDMDFV RFIINCFKVY
YPKYLSKMVI FDMPWIMNAA FKIVKTWLGP EAVSLLKFTS KNDIQDYVSV EYLPPHMGGT
DPFKYSYPPL VDDDFQTPLC ENGPIASEDE ASSKEDIESD GKDTLETISN EEQTTLPKKG
NIMEPTSKAD ENEKVDSKMK TFKKPLSVFK GPLLHISPAE ELYFGSTDSG EKKALIVLTN
VTKNIVAFKV RTTAPEKYRV KPSNSSCDPG ASVDIVVSPH GGLTVSAQDR FLVMAAEMEQ
TSGTGPAELT QFWKEVPRNK VMEHRLRCHI VDSYKPSSLT WKDHAFNMSV KTSEDLCHQL
SRLVASTRKL EDQVQQCIRF QQLLLALTVL LLTFMVSFFY LLHG
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