ID W5PU71_SHEEP Unreviewed; 625 AA.
AC W5PU71;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Cilia- and flagella-associated protein 206 {ECO:0000256|ARBA:ARBA00021602};
GN Name=CFAP206 {ECO:0000313|Ensembl:ENSOARP00000014002.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000014002.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000014002.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000014002.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000014002.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
CC -!- SIMILARITY: Belongs to the CFAP206 family.
CC {ECO:0000256|ARBA:ARBA00010500}.
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DR EMBL; AMGL01107386; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01107387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01107388; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01107389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PU71; -.
DR STRING; 9940.ENSOARP00000014002; -.
DR PaxDb; 9940-ENSOARP00000014002; -.
DR Ensembl; ENSOART00000014209.1; ENSOARP00000014002.1; ENSOARG00000013071.1.
DR eggNOG; ENOG502QTGJ; Eukaryota.
DR HOGENOM; CLU_030061_0_0_1; -.
DR OMA; LHDTVRY; -.
DR Proteomes; UP000002356; Chromosome 8.
DR Bgee; ENSOARG00000013071; Expressed in fallopian tube and 45 other cell types or tissues.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR InterPro; IPR021897; FAP206.
DR PANTHER; PTHR21442:SF0; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206; 1.
DR PANTHER; PTHR21442; UNCHARACTERIZED; 1.
DR Pfam; PF12018; FAP206; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT COILED 290..317
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 625 AA; 71473 MW; F81755CF702E0A3D CRC64;
MPPTQAESVI KNIIREIGQE CAAHGEIVPE TLVAFMVKAV VLDPSNGFNT DRTLTKSDVQ
KLVKLCVNRL LDSKNPSLDT IKMQVYFDMN YTSREEFLEE HHRVIESRLS SVSREITDSR
ACVREELESL YRKIVSYVLL RSGLGSPTDI KIVREATAAL QSVFPQTELG TFLTLSKKDK
ERQLKELTMI VTGIRLFNRD CGKGGEGIDD CRPVPAILQE AIPATTQHVD SQLEAVQDQA
YRYTAILEKA AKNPLMSQEL QPYMLREALY NVRQCEIFLQ VILSDIITCA QEVEMMIKQL
EAQLEQLKLT VKSKTAIPTS QVFPIFIALS NLWTSFQDET VLISILSNLT THLEPFLGAH
DLFFPEKVMQ VLLDGVTVKT DVCRIKEHIE DKVNVADFKK LEWLFPETTA NFDKLLIQYR
GFCAYTFATT DGLLLPGNPS IGILKYKDKY YTFNTRDAAY SFAENPENYI DIIREKAKKN
AELIQLLELH QQFETFIQYS QMKEVDKRYI KPITKCETGT QTDTHLLPPT IVRSYEWNEW
ELRRKAIKLA NLRRKVTHSV QTDHSHMRRE NYSQVYPSKD VGTQSMREGS SRVPRPQIYI
AGLRGGQTKT TYGVKVNLTR AVDET
//
