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Database: UniProt
Entry: W5PUI5_SHEEP
LinkDB: W5PUI5_SHEEP
Original site: W5PUI5_SHEEP 
ID   W5PUI5_SHEEP            Unreviewed;       407 AA.
AC   W5PUI5;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   16-OCT-2019, entry version 33.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOARP00000014117};
GN   Name=FLI1 {ECO:0000313|Ensembl:ENSOARP00000014117};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
OC   Pecora; Bovidae; Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000014117, ECO:0000313|Proteomes:UP000002356};
RN   [1] {ECO:0000313|Ensembl:ENSOARP00000014117, ECO:0000313|Proteomes:UP000002356}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000014117,
RC   ECO:0000313|Proteomes:UP000002356};
RX   PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA   Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA   Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
RA   Wang J., Wang W., Xun X.;
RT   "The sheep genome reference sequence: a work in progress.";
RL   Anim. Genet. 41:449-453(2010).
RN   [2] {ECO:0000313|Ensembl:ENSOARP00000014117}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2014) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; AMGL01061384; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01061385; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01061386; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01061387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AMGL01061388; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9940.ENSOARP00000014117; -.
DR   Ensembl; ENSOART00000014324; ENSOARP00000014117; ENSOARG00000013176.
DR   GeneTree; ENSGT00940000158261; -.
DR   OMA; GWGSNMN; -.
DR   Proteomes; UP000002356; Chromosome 21.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR   GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0009887; P:animal organ morphogenesis; IEA:Ensembl.
DR   GO; GO:0008015; P:blood circulation; IEA:Ensembl.
DR   GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
DR   CDD; cd08541; SAM_PNT-FLI-1; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR035575; Fli-1.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR035573; SAM_PNT-FLI-1.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF161; PTHR11849:SF161; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002356};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT   DOMAIN       67    153       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      236    316       ETS. {ECO:0000259|PROSITE:PS50061}.
FT   REGION      160    227       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      388    407       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    183    227       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   407 AA;  46336 MW;  5BBA02FB8DB264C7 CRC64;
     HKMNPPPPQQ EWMNQPVRVN VKREYDHMNG SRESPVDCSV SKCGKLVGGG ESNTMSYNSY
     MDEKNGPPPP NMTTNERRVI VPADPTLWTQ EHVRQWLEWA IKEYSLMEID TSFFQNMDGK
     ELCKLNKEDF LRATSLYNTE VLLSHLSYLR ESSLLAYNTT SHTDPSSRLN VKEDPSYDSV
     RRGGWGSNMN SGLNKSPPLA GAQTMSKNTE QRPQPDPYQI LGPTSSRLAN PGSGQIQLWQ
     FLLELLSDSA NASCITWEGT NGEFKMTDPD EVARRWGERK SKPNMNYDKL SRALRYYYDK
     NIMTKVHGKR YAYKFDFHGI AQALQPHPTE SSMYKYPSDI SYMPSYHTHQ QKVNFVPPHP
     SSMPVTSSSF FGAASQYWTS PTGGIYPNPN VPRHPNTHVP SHLGSYY
//
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