ID W5PYR2_SHEEP Unreviewed; 360 AA.
AC W5PYR2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=MRG domain-containing protein {ECO:0000259|Pfam:PF05712};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000015597.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000015597.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000015597.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000015597.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AMGL01118330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5PYR2; -.
DR SMR; W5PYR2; -.
DR STRING; 9940.ENSOARP00000015597; -.
DR PaxDb; 9940-ENSOARP00000015597; -.
DR Ensembl; ENSOART00000015828.1; ENSOARP00000015597.1; ENSOARG00000014539.1.
DR eggNOG; KOG3001; Eukaryota.
DR HOGENOM; CLU_039566_4_0_1; -.
DR Proteomes; UP000002356; Chromosome X.
DR Bgee; ENSOARG00000014539; Expressed in testis and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.274.30; MRG domain; 1.
DR InterPro; IPR008676; MRG.
DR InterPro; IPR038217; MRG_C_sf.
DR InterPro; IPR026541; MRG_dom.
DR PANTHER; PTHR10880; MORTALITY FACTOR 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR10880:SF48; MRG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05712; MRG; 1.
DR PROSITE; PS51640; MRG; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 186..349
FT /note="MRG"
FT /evidence="ECO:0000259|Pfam:PF05712"
FT REGION 123..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 360 AA; 40849 MW; 4FA859BC32CE4C7D CRC64;
DSESKLQECE RVLCLHGRLP YENEVTKSCQ KDNQATYYTR YSGWNRKSLK VAKKTTKRHT
THVIVVGIGS RNQGPQAHGS QSAEARAEWT SKSQVLKYSP AMDLNLQTQG KLQRATQEWY
AEEKKGRCRR GSTPGKKPGA MHQQINVEVK TTKNPQKTGD GGSSSETPQP RCHRRAQVDP
MTEGLKSFLS RMDVKVTSPE ILTRWLVDDS ELTSKFQVLK HLPDTKKDMD SILVSKDNFK
EPVRSIHNKE HAINEVARIK GYFIVMLGTQ VLYKFERPYA EILVDHSDAS MSQVYGASHL
LRLFVRIGAM LAYTPLDEKS LALLLNYLHD FLKYQAKNST TLFIASDYEV ALRVPLESCV
//
