ID W5Q155_SHEEP Unreviewed; 928 AA.
AC W5Q155;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=SEA domain-containing protein {ECO:0000259|PROSITE:PS50024};
GN Name=LOC101122753 {ECO:0000313|Ensembl:ENSOARP00000016441.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000016441.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000016441.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000016441.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000016441.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGL01069423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5Q155; -.
DR STRING; 9940.ENSOARP00000016441; -.
DR PaxDb; 9940-ENSOARP00000016441; -.
DR Ensembl; ENSOART00000016676.1; ENSOARP00000016441.1; ENSOARG00000015326.1.
DR eggNOG; ENOG502SEXN; Eukaryota.
DR HOGENOM; CLU_314948_0_0_1; -.
DR OMA; NMTTMPG; -.
DR Proteomes; UP000002356; Chromosome 24.
DR Bgee; ENSOARG00000015326; Expressed in rectum and 16 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.960; SEA domain; 1.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR PANTHER; PTHR37999; MUCIN-17; 1.
DR PANTHER; PTHR37999:SF2; MUCIN-17; 1.
DR Pfam; PF01390; SEA; 1.
DR SMART; SM00200; SEA; 1.
DR SUPFAM; SSF82671; SEA domain; 1.
DR PROSITE; PS50024; SEA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002356};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 827..850
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 617..735
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT REGION 105..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 928 AA; 98113 MW; ACB2B804BCFBA0CB CRC64;
MVRQNPQSLL RVLTQHLFSL NPQSLLKAPT LQSLGAPPLL LVSLSLLNLL RVPSPQSLGI
LPPRLVGLNP SSLQRVPKPR LVILNPQGGS DFTVSSEASL TTVLWSSPTT SGGPESTVSS
ESSYTAAPGN TITTSDQSES TESSEGSYTT SGQSESSVSS AGSHTTGPGS STTTGLSEST
VSSDGSHTTI PLSSPATSGL SEFTMSPEGS LTTRPGSFAT TSGWSASSVS SESSHTGVAE
SSTAPSSTGG ISSSSSGSVQ STTSVTQKST DHNTISDFSQ VTDLPTSTTS QEDGSPVSTS
SPAESITSSS GDEERTTYST PEATVSTIVS APSTDTVSSY TSTFYIPSNS EGLSTTTSRT
DLSTTTITEI SSVLSTISES SMSASYPSHS SSLASSSIPS LLSTTPSVST QTITGLTEGL
TLATSTPDSS KPTGTLSSTV TAGNEISAST SRPGESLTTS TGDGHMTTSS SLGSTLYTSS
SDGSLPSFST HSLHSTNHAS PSSSSPSETS THTVVSQHTT TTAKEESTSG FSSPVASTSP
GSTGTTVPGF STTSTLHPPF TRTQTTVRTT HSSTMTPLQC YNNATWNGKE CVCAQGYFGY
QCKDVREYFF IETPQKINAT IDLRVKVTNR NFTDDLNDKS SDAYKNFVQV FKSQMDKVYR
GNNFPQYRGV NVIRLLPGSI VVEHEVIMEA NYTSGYLELF ENLTKIVKAK IMNETTQLHG
NSKDCKNLSL LCYDETATIV NPVKVGFDPQ EQCTKNSPKE FSQFYYIEEL DGKLACVTKC
TPGTKSKMDC HHGTCQLQQS GPRCLCLSSD THWYSGETCE SSTSKSMVYG IVGALGALLV
VLVVVLIFLL GRSQRKLHSR QEYDMSREWQ DADYPGSFEN TSVWEGEDLK GDTFGLENIY
RNFQPSLGSV DPTTELHIQK PTVVTTAQ
//
