ID W5QC32_SHEEP Unreviewed; 926 AA.
AC W5QC32;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Calcium homeostasis endoplasmic reticulum protein {ECO:0008006|Google:ProtNLM};
GN Name=CHERP {ECO:0000313|Ensembl:ENSOARP00000020279.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000020279.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000020279.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000020279.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000020279.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01090921; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01090922; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01090923; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01090924; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5QC32; -.
DR SMR; W5QC32; -.
DR STRING; 9940.ENSOARP00000020279; -.
DR PaxDb; 9940-ENSOARP00000020279; -.
DR Ensembl; ENSOART00000020559.1; ENSOARP00000020279.1; ENSOARG00000018876.1.
DR eggNOG; KOG4368; Eukaryota.
DR HOGENOM; CLU_009446_0_0_1; -.
DR OMA; QNTHHDI; -.
DR Proteomes; UP000002356; Chromosome 5.
DR Bgee; ENSOARG00000018876; Expressed in ileocolic lymph node and 52 other cell types or tissues.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006874; P:intracellular calcium ion homeostasis; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.10.10.790; Surp module; 1.
DR InterPro; IPR039037; CHERP.
DR InterPro; IPR006569; CID_dom.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR000061; Surp.
DR InterPro; IPR035967; SWAP/Surp_sf.
DR PANTHER; PTHR12323:SF0; CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN; 1.
DR PANTHER; PTHR12323; SR-RELATED CTD ASSOCIATED FACTOR 6; 1.
DR Pfam; PF04818; CID; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF01805; Surp; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00648; SWAP; 1.
DR SUPFAM; SSF109905; Surp module (SWAP domain); 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50128; SURP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 15..57
FT /note="SURP motif"
FT /evidence="ECO:0000259|PROSITE:PS50128"
FT DOMAIN 827..877
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 79..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 900..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..96
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..209
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..372
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..442
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..496
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..527
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..613
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..775
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..802
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 926 AA; 104158 MW; 9CAE0FCAFCFC7E8C CRC64;
MEMPLPPDDQ ELRNVIDKLA QFVARNGPEF EKMTMEKQKD NPKFSFLFGG EFYSYYKCKL
ALEQQQLICK QQAPELEPAA TLPPLPQPPL APAAPVAPAQ GTPSMDELIQ QSQWNLQQQE
QHLLALRQVS FFAAAHTLHC PECTLLQESS HGASWLILCP SPETCLPSPP SAPKTWGAPI
LTHARSGPAA APHLRPAPTE RPPHPADLMP RPLIARVLPR GSQRKQAREL LAALQKVVVP
IYCTSFLAVE EDKQQKIARL LQLWEKNGYF DDSIIQQLQS PALGLGQYQA TLITEYSSVV
QPVQLAFQQQ IQTLKTQHEE FVNSLTQQQQ QQQQQQQQQI QMPQMEADVK ATPPPPAPPP
APTPPTQPDD SKPPIQMPGS SEYDASGGVQ DPAASGPRGP GPHDQIPPNK PPWFDQPHPV
APWGQQQPPE QPPYPHHQGG PPHCPPWNNS HEGMWGEQRG DPGWNGQRDA PWNSQPDPNW
NSQFEGPWNS QHEQPPWGGG QREPPFRMQR PPHFRGPFPP HQQHPQFNQP PHPHNFNRFP
PRFMQDDFPP RHPFERPPYP HRFDYPQGDF QAEMGPPHHH PGHRMPHPAI NEHPPWGGPQ
HPDFGPPPHG FNGQPPHMRR QGPPHINHDD PSLVPNVPYF DLPAGLMAPL VKLEDHEYKP
LDPKDIRLPP PMPPSERLLA AVEAFYSPPS HDRPRNSEGW EQNGLYEFFR AKMRARRRKG
QEKRNSGPSR SRSRSKSRGR SSSRSNSRSS KSSGSYSRSR SRSCSRSYSP SRSRSSRSRS
RSRSRSRSKS YSPGRRHRSR SRSPTPPSSA GLGSNSAPPI PDSRLGEENK GHQMLVKMGW
SGSGGLGVKE QGIQDPIKGG DVRDKWDQYK GVGVALDDPY ENYRRNKSYS FIARMKAREE
CKRSSRHHEG VPSPRGHKLI SPDSEA
//
