ID W5QCL2_SHEEP Unreviewed; 598 AA.
AC W5QCL2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=RabBD domain-containing protein {ECO:0000259|PROSITE:PS50916};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000020459.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000020459.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000020459.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000020459.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AMGL01000482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01000483; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01000484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMGL01000485; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5QCL2; -.
DR SMR; W5QCL2; -.
DR PaxDb; 9940-ENSOARP00000020459; -.
DR Ensembl; ENSOART00000020741.1; ENSOARP00000020459.1; ENSOARG00000019048.1.
DR eggNOG; ENOG502RJPZ; Eukaryota.
DR HOGENOM; CLU_025193_2_0_1; -.
DR OMA; EAQGWLC; -.
DR Proteomes; UP000002356; Chromosome 1.
DR Bgee; ENSOARG00000019048; Expressed in abomasum and 42 other cell types or tissues.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd15752; FYVE_SlaC2-a; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041282; FYVE_2.
DR InterPro; IPR037442; Melanophilin_FYVE-rel_dom.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR14555:SF1; MELANOPHILIN; 1.
DR PANTHER; PTHR14555; MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED; 1.
DR Pfam; PF02318; FYVE_2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50916; RABBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 4..124
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT REGION 153..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..383
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 400..416
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..542
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..566
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 64888 MW; 4276102EA12CC45F CRC64;
MGKTLDLSKL TDEEAKHVWE VVQRDFDLRR KEEERLEGLK GKIKKENSKR ELLSDTAHLN
TTHCAHCLQP YRLLETPKRQ CLECHLFTCR GCSHPHPEEQ GWLCDPPPPA TVVKMGSLEW
YYGHVRARFK RFGSAQVVRS LCGRLQRGGL PDGVRIAPDV RKSRGEGALG GPLPSSSPRL
KSAPPPIRLT LPPLSLESLP AQKKRLLPIH GWDFEADSDD SDPSCGHPPS LSSVSGATDG
LQALTDDPCA EETTPQEAGI LDQADARAPG CHPRPEEQRV GLSPAGLDEL SELCLPGESC
TAGPGVAATP RTNILRNEQL PSQYLADVDT SDEESIWTQR VASHHPRQKG WAASESQHPG
GDEPTDADAE EAALKRKLEE LTSHISDQGV SSAEEEEGTD AGAEMGRNKT VEDHPGATWE
VRPAAGQTPS CGKDLLSPGD PEQPSRTTEA ELVEPGGGGG GGGGGKGAAT TREVRRTESQ
VSNIKSRIAA LQAAGLTVRP SGKPQRKSNL PIFLPRLVRK SDQSLKDPHA DPSDEAKVEA
VPCLVRRKLS NYPKSQDKDD DSFSRKSMYR GSLTQRNPNG RKRAANHSFA KPVMTHQP
//
