ID W5QD16_SHEEP Unreviewed; 197 AA.
AC W5QD16;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Myosin light chain 1/3, skeletal muscle isoform {ECO:0000256|ARBA:ARBA00039878};
DE AltName: Full=Myosin light chain alkali 1/2 {ECO:0000256|ARBA:ARBA00041959};
GN Name=MYL1 {ECO:0000313|Ensembl:ENSOARP00000020614.1};
OS Ovis aries (Sheep).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Ovis.
OX NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000020614.1, ECO:0000313|Proteomes:UP000002356};
RN [1] {ECO:0000313|Ensembl:ENSOARP00000020614.1, ECO:0000313|Proteomes:UP000002356}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000020614.1,
RC ECO:0000313|Proteomes:UP000002356};
RX PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
RA Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
RA Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C., Wang J.,
RA Wang W., Xun X.;
RT "The sheep genome reference sequence: a work in progress.";
RL Anim. Genet. 41:449-453(2010).
RN [2] {ECO:0000313|Ensembl:ENSOARP00000020614.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Non-regulatory myosin light chain required for proper
CC formation and/or maintenance of myofibers, and thus appropriate muscle
CC function. {ECO:0000256|ARBA:ARBA00037734}.
CC -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains. Does
CC not bind calcium. {ECO:0000256|ARBA:ARBA00038595}.
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DR EMBL; AMGL01055655; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; W5QD16; -.
DR SMR; W5QD16; -.
DR STRING; 9940.ENSOARP00000020614; -.
DR PaxDb; 9940-ENSOARP00000020614; -.
DR Ensembl; ENSOART00000020897.1; ENSOARP00000020614.1; ENSOARG00000019190.1.
DR eggNOG; KOG0030; Eukaryota.
DR HOGENOM; CLU_061288_13_0_1; -.
DR OMA; NPTNEEM; -.
DR Proteomes; UP000002356; Chromosome 2.
DR Bgee; ENSOARG00000019190; Expressed in longissimus thoracis muscle and 30 other cell types or tissues.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23048; MYOSIN LIGHT CHAIN 1, 3; 1.
DR PANTHER; PTHR23048:SF3; MYOSIN LIGHT CHAIN 1_3, SKELETAL MUSCLE ISOFORM; 1.
DR Pfam; PF13405; EF-hand_6; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002356}.
FT DOMAIN 53..88
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 130..165
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..36
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 197 AA; 21488 MW; F3E0418139EF7E9C CRC64;
ILLNKMAPKK DVKKPAAAAA PAPAPAPAPA PAPAPPKEEK IDLSAIKIEF SKQQQDEFKE
AFLLYDRTGD GKITLSQVGD VLRALGTNPT NAEVKKVMGN PSNEEMNAKK IEFEQFLPML
QAISNNKDQG TYEDFVEGLR VFDKEGNGTV MGAELRHVLA TLGEKMKEEE VEALMAGQED
SNGCINYEAF VKHIMSN
//
