ID W5S5Q1_9VIRU Unreviewed; 396 AA.
AC W5S5Q1;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Cyclin-dependent kinase {ECO:0000313|EMBL:AHH02004.1};
GN ORFNames=pv_438 {ECO:0000313|EMBL:AHH02004.1};
OS Pithovirus sibericum.
OC Viruses; Pithoviruses; Pithovirus.
OX NCBI_TaxID=1450746 {ECO:0000313|EMBL:AHH02004.1, ECO:0000313|Proteomes:UP000202176};
RN [1] {ECO:0000313|EMBL:AHH02004.1, ECO:0000313|Proteomes:UP000202176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1084-T {ECO:0000313|EMBL:AHH02004.1};
RX PubMed=24591590; DOI=10.1073/pnas.1320670111;
RA Legendre M., Bartoli J., Shmakova L., Jeudy S., Labadie K., Adrait A.,
RA Lescot M., Poirot O., Bertaux L., Bruley C., Coute Y., Rivkina E.,
RA Abergel C., Claverie J.M.;
RT "Thirty-thousand-year-old distant relative of giant icosahedral DNA viruses
RT with a pandoravirus morphology.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:4274-4279(2014).
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DR EMBL; KF740664; AHH02004.1; -; Genomic_DNA.
DR RefSeq; YP_009001339.1; NC_023423.1.
DR GeneID; 18266465; -.
DR KEGG; vg:18266465; -.
DR OrthoDB; 8955at10239; -.
DR Proteomes; UP000202176; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00180; PKc; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR006671; Cyclin_N.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR44167; OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED; 1.
DR PANTHER; PTHR44167:SF8; OVARIAN-SPECIFIC SERINE_THREONINE-PROTEIN KINASE LOK; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SUPFAM; SSF47954; Cyclin-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:AHH02004.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000202176};
KW Transferase {ECO:0000313|EMBL:AHH02004.1}.
FT DOMAIN 2..262
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 33
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 396 AA; 44772 MW; F88EE1D24F069680 CRC64;
MISYLSKIGQ GSYSSVYLAE LTEGNEKMQV AVKCLDSKYG LETPWELEIL SKERSPYLLH
SISTIKHGNG IAIVLPLAKV TLRQFLQARP TFSAMETIIS NIFSGMAALH CSGFYHLDFK
SDNVLVFDDR AVICDFSLSL PKTFWGVRKE VVTITSRPPE LLFQANNQLV QLSDKIDSWS
MGIVILEILT GFHLRSRSGP AAYSEIQKMF SDQNRRTTLT SLLSSSPYPE QAIAYLEILE
SLLDPNPATR KSICSFFPVE KVGVERNVLY SYREKLIFCY DWIEKLCRSF QTQWSTYLNA
MTLLEEFTDH KQDITSRSKL LAYSLAAMKL SIQLEEEITL DYRSLITCTG GALSEMDLVL
AEQDLVLTLG SPLHRQVLKS PLPHLTNSDL QNRMSS
//
