ID W5TIS4_9NOCA Unreviewed; 520 AA.
AC W5TIS4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040298};
GN ORFNames=NONO_c23550 {ECO:0000313|EMBL:AHH17151.1};
OS Nocardia nova SH22a.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1415166 {ECO:0000313|EMBL:AHH17151.1, ECO:0000313|Proteomes:UP000019150};
RN [1] {ECO:0000313|EMBL:AHH17151.1, ECO:0000313|Proteomes:UP000019150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH22a {ECO:0000313|EMBL:AHH17151.1};
RX PubMed=24747905;
RA Luo Q., Hiessl S., Poehlein A., Daniel R., Steinbuchel A.;
RT "Insights into the Microbial Degradation of Rubber and Gutta-Percha by
RT Analysis of the Complete Genome of Nocardia nova SH22a.";
RL Appl. Environ. Microbiol. 80:3895-3907(2014).
CC -!- FUNCTION: Probable oxidoreductase that may play a role as regulator of
CC mitochondrial function. {ECO:0000256|ARBA:ARBA00037217}.
CC -!- SUBUNIT: Interacts with COX5B; this interaction may contribute to
CC localize PYROXD2 to the inner face of the inner mitochondrial membrane.
CC {ECO:0000256|ARBA:ARBA00038825}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC {ECO:0000256|ARBA:ARBA00004305}.
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DR EMBL; CP006850; AHH17151.1; -; Genomic_DNA.
DR RefSeq; WP_025348631.1; NZ_CP006850.1.
DR AlphaFoldDB; W5TIS4; -.
DR STRING; 1415166.NONO_c23550; -.
DR KEGG; nno:NONO_c23550; -.
DR PATRIC; fig|1415166.3.peg.2406; -.
DR eggNOG; COG1233; Bacteria.
DR HOGENOM; CLU_019327_2_0_11; -.
DR OrthoDB; 9774675at2; -.
DR Proteomes; UP000019150; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.90.660.50; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR10668; PHYTOENE DEHYDROGENASE; 1.
DR PANTHER; PTHR10668:SF103; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019150}.
FT DOMAIN 13..282
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 520 AA; 55266 MW; 704F126B862DBC0E CRC64;
MTTLIIGSGH NALVAACYLA RAGHPVEVLE RDEVLGGAVS TVERFPGHLV DRGSSAHIMI
RHTGIIEELE LARFGLRYID CDPWAFAPAP PGSGAVPIVF HRDVARTCAA IERACGARDA
DAYRRFVAVW GPRAQRVMRS FGGAATAGRF VRSFWGLDAR GGASGLSREF LQSGDALLDT
WFDDERLKAA LAWFGAQSGP PMSEPGTAPM AGFAALMHTL PPGRAIGGSG ALTTALVARL
RADGGVVSAG DAVTELRRAG DGWRVRTAAG RDLFARTVIS GAHVLTTLDL LRRGGFDGAV
IDDWRRRIRV GPGIGMVVRA ATTALPAYSG ATAAESARGL QLLVTDRRQL RLAHAAALAG
DLPPRPAVLA MSFSALDPTI APPGEHQLSL WAQWHPHRLA DGSAWSAHGE READRIIAEV
DALAPGFADS VRQRFVQTPA DLERELGLIG GNVMHVEMSL DQMFFWRPLP ELSDQRVPGA
PGLYLTGAST HPGGGVSGAS GRTAAQLVAR TLRRGRFARR
//
