ID W5TM50_9NOCA Unreviewed; 471 AA.
AC W5TM50;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Putative metabolite transport protein {ECO:0000313|EMBL:AHH18326.1};
GN ORFNames=NONO_c35390 {ECO:0000313|EMBL:AHH18326.1};
OS Nocardia nova SH22a.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=1415166 {ECO:0000313|EMBL:AHH18326.1, ECO:0000313|Proteomes:UP000019150};
RN [1] {ECO:0000313|EMBL:AHH18326.1, ECO:0000313|Proteomes:UP000019150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH22a {ECO:0000313|EMBL:AHH18326.1};
RX PubMed=24747905;
RA Luo Q., Hiessl S., Poehlein A., Daniel R., Steinbuchel A.;
RT "Insights into the Microbial Degradation of Rubber and Gutta-Percha by
RT Analysis of the Complete Genome of Nocardia nova SH22a.";
RL Appl. Environ. Microbiol. 80:3895-3907(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP006850; AHH18326.1; -; Genomic_DNA.
DR AlphaFoldDB; W5TM50; -.
DR STRING; 1415166.NONO_c35390; -.
DR KEGG; nno:NONO_c35390; -.
DR PATRIC; fig|1415166.3.peg.3629; -.
DR eggNOG; COG0477; Bacteria.
DR HOGENOM; CLU_001265_39_5_11; -.
DR Proteomes; UP000019150; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17369; MFS_ShiA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR43045:SF2; INNER MEMBRANE METABOLITE TRANSPORT PROTEIN YHJE; 1.
DR PANTHER; PTHR43045; SHIKIMATE TRANSPORTER; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019150};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 25..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..453
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 471 AA; 50086 MW; 58FEFB29553A8B9F CRC64;
MLDTVTVETT EPTTDSVPAN RRSRVVIASL IGTSIEFYDF YIYGTAAVLV FPKLFFPHES
PTAAQLSSFV TFALAFFARP IGSVVFGHFG DRIGRKRTLV SSLLIMGTAT VLIGCLPTYA
VAGLWAPVLL AVLRFVQGVG LGGEWSGATL LATENAPEGR RGLFGSLPQL GAPIGFFLAN
GVFLLLTAIM PAHSDDPGAI TFDNVGWRIP FLLSAILVVV GLYVRLQIVE SRVFTDVAAA
DNIARVPATR LVRTHWRHLV LGTLLCVSTY VLFYLMTTFT LTYGTAAAHP ASDAKAGLGF
SRTEFLTILL VGVVFFAVFT TVAGLLTDRV GRRRTLLVTL VAVAVFGVLF QPWFTTAGSV
PLSVSFVIVG LALMGLSYGP MGSLLPELFP ADVRYTGSAV VYNLAGVLGA SLAPIIAVAL
WRPDGNIAKV GLYLSAAGVL SLLALLGVRE TRDIDYTAQT PPSERPPAPV G
//
