ID W5U5L7_ICTPU Unreviewed; 297 AA.
AC W5U5L7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Syntaxin-4 {ECO:0000313|EMBL:AHH37236.1, ECO:0000313|RefSeq:XP_017339522.1};
GN Name=STX4 {ECO:0000313|EMBL:AHH37236.1};
GN Synonyms=stx4 {ECO:0000313|RefSeq:XP_017339522.1,
GN ECO:0000313|RefSeq:XP_017339523.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH37236.1};
RN [1] {ECO:0000313|EMBL:AHH37236.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH37236.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017339522.1, ECO:0000313|RefSeq:XP_017339523.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017339522.1,
RC ECO:0000313|RefSeq:XP_017339523.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063, ECO:0000256|RuleBase:RU003858}.
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DR EMBL; JT405576; AHH37236.1; -; mRNA.
DR RefSeq; XP_017339522.1; XM_017484033.3.
DR RefSeq; XP_017339523.1; XM_017484034.3.
DR STRING; 7998.ENSIPUP00000000847; -.
DR Ensembl; ENSIPUT00000000907; ENSIPUP00000000847; ENSIPUG00000000613.
DR GeneID; 108274127; -.
DR KEGG; ipu:108274127; -.
DR CTD; 6810; -.
DR OMA; NTMQSEY; -.
DR OrthoDB; 2876074at2759; -.
DR Proteomes; UP000221080; Chromosome 13.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd00179; SynN; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 1.20.58.70; -; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR InterPro; IPR006011; Syntaxin_N.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; SYNTAXIN; 1.
DR PANTHER; PTHR19957:SF97; SYNTAXIN-4; 1.
DR Pfam; PF05739; SNARE; 1.
DR Pfam; PF00804; Syntaxin; 1.
DR SMART; SM00503; SynN; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 201..263
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 47..98
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 297 AA; 33918 MW; 98359DA481DFB26A CRC64;
MRDRTKELGN PADGSDEDEE GTALMFKPGT GTSVKEDRDN EGFFRKVHEI REGLESLKKK
VSELENKQKS VLSEALPKES MKKELQTIRD EIKVLATQIQ KKLKSIEPKK IDEDGKYVPI
NLRMQRTQHA VLSRNFIESM SYCNTIQSQY RDRNVERIQR QLKITGNNVT DEQLEAMLES
GQTDVFTQNI LTDAQATRQA LNEIESRHDE ILKLEKSIRD LHDMFQYLAM EVEAQGEMVD
RIENNIINSS NYVEKAVEDT GAAVVSRNKA RKKKMWIAVC IAILVLIIAI ALAVSFS
//
