ID W5UAP6_ICTPU Unreviewed; 2215 AA.
AC W5UAP6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Protein sidekick-1 {ECO:0000313|EMBL:AHH38649.1, ECO:0000313|RefSeq:XP_017310201.1};
GN Name=SDK1 {ECO:0000313|EMBL:AHH38649.1};
GN Synonyms=sdk1a {ECO:0000313|RefSeq:XP_017310201.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH38649.1};
RN [1] {ECO:0000313|EMBL:AHH38649.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH38649.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017310201.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017310201.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; JT409373; AHH38649.1; -; mRNA.
DR RefSeq; XP_017310201.1; XM_017454712.3.
DR STRING; 7998.ENSIPUP00000026784; -.
DR Ensembl; ENSIPUT00000027885; ENSIPUP00000026784; ENSIPUG00000017988.
DR GeneID; 108257186; -.
DR KEGG; ipu:108257186; -.
DR CTD; 558391; -.
DR OrthoDB; 2874985at2759; -.
DR Proteomes; UP000221080; Chromosome 24.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 13.
DR Gene3D; 2.60.40.10; Immunoglobulins; 19.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 13.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13927; Ig_3; 2.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 13.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 6.
DR SUPFAM; SSF49265; Fibronectin type III; 7.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 13.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 2: Evidence at transcript level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2006..2029
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 104..186
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 293..372
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 386..476
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 480..569
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 574..662
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 669..765
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 770..866
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 871..970
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 974..1068
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1072..1171
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1176..1274
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1279..1376
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1380..1474
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1479..1576
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1581..1697
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1702..1798
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1802..1899
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1900..1999
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 8..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1261..1280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2196..2215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2215 AA; 244051 MW; 0846E5F151AB7698 CRC64;
MEIVQCLRGG PESGRRRAAS RDNARLFGSA RSSDPGDKCS SGRGAAKSNT KGTSGVRKRT
GDMSDTVRSF RRSRKLGMCM RSYWALICLQ IHVLKAHAQG DVAPYFKTEP GPPEIHLEGN
RLVMTCLAEG SWPLEFKWIL NNTDITAFSP EYKYIIPSLQ RSDMGVYQCV VRNRMGALLQ
RRAEIQVAYM GDFVEADQHK TVTQGRAAIL NSPDISSFPR PQVTWFRDGY KIIPSSRVAI
TMENQLVVLA TAAMDAGRYY VQAVNEKNGE NKTSPSIYLN VADGEASVDP VAPVIVIPPR
NTTVVAGVSE ATLECVANAR PVDKLSLVWR RNGVEVASGV GSFGRRLTIV NPTTVDMGLY
VCEASLLDSS VKPAEARAFL SIIETPYFTA EPRRKMMGEV EKSMDIPCQA RGVPMPKLEW
YKDAVPLSKL NNPRYKVISS MGLQIRRLQP NDAGIFQCFA RNAAGELQVH TYLDVTSITP
AFSAPPVNIN VTDGAVASFT CQVSGAPKPS ITWRKDARIL ASGSVQIPRF MLLESGGLQV
QPVALQDAGT YTCYAANSEG VINASAELTV WSRTYISQPP VDRRVIKGTT AILECGAIHD
ARVHVRFVWM KGGEMVGQSK GGRISVQQGS LHISQTWSGD IGDYTCDVIS LAGNDSKTAR
LEVIELPHSP RNLQAGLNAT DSRSVHLSWM RPFDGNSPLL HYIVELSENN SPWRVYLPNV
DPMLTTAEVT GLTPARTYQF RVCAVNQVGK GQYSGETNRL MLREEPPSAP PKNIVASGRT
NQSIMVQWQP PPELQLNGVL RGYVLRYRLA GLPGEYQQQN ITSPDINYCL ITELIIWTQY
EIQVAAYTGA GLGVFSQPVV EYTLQGVPTA PPQDVEAVAV NSTTIKFTWN PPPQQFINGI
NQGYKLMVWP ERSPEATTVV TITPDYHGTR HQGYITGLKK FTWYLTSVLC FTTPGNGPRS
ATKLVQTHED IPGPVGRLSF TEILDTSLRV SWEEPVEKNG IITGYMLSWE AQGLKESRVE
RTMPNSTLEY KVTGLTSLTT YTLEVAAMTS AGMGMLSSST ISSGVPPELP GPPSNLQISK
ISPRSATLKF RAGDDGKTSI SKWIVEGQVG STGEEEEWKV LYEKENDPEA QVLEVPNLTP
FTHYRFRMRQ ANIVGSSEVS EPSRVIQTLQ APPDVAPGSV SVRTASETSV WLRWVPLPET
EYNGNPESVG YRVRVWRADQ QGDASTRVVN DRLEREITLE GLEEWTEYLF QIQAFNSIGP
GPWSEPVKGR TRESVPSGAP ENVTAEAMSS THMLVTWGPV PEPQQNGNIL GYKVLYQEKD
SGTEPQVHLV KGNLTQSVLL RNLRKYVQYE IQVLAFTRIG DGQLSSPSVL ERTKDDVPGP
PMRLVFPEVR LKEVRVVWQP PVDPNGIIMG YQVAYRLDSG DPNKFTTVEV GANTTQFTAS
GLLPESAYIF RISAKTQQGW GTAAQAVVIT TEIRERPQPP LQLSVPQDQV QSRQLKLDWV
PGGDGSSPVR YFTLQLRQLP DGNWITHSSS ISHNSTSYVV DRLKPYTSYK LRMMATNDIG
DSKYSRETDA ITTLQDVPDE APVIQSVKPS TTTSVLVQWQ PPKEESVNGV LVGYRLYYRE
LQYDSMPQEA KKTINSTSAR ADLTAKSTVK TVSNPSLTEF ELTQLQKYQR YEIVMTAYNI
IGESPASAPV EVFVGEAAPS VAPQNIQVNT VSSTQLEVQW EPPPVETQNG IIQGYKIHYW
EMDNQNETEK VKILFLPETS VRLKNLTSYT YYMVKLSAFN AAGDGPLSEP RRGRTLQSAP
SAPSFITFSE ITSTTLNVSW GFPVSPNGVV EGYRVVYEPT APIHGISKVV TVDIRGSWQR
WLKVRDLTKG VTYCFRVQAK TIGYGPEAEA NITAGPVQGS PGSPLKTSVT KSGSGLTIQW
IPGDTGTGHV TGYVIEARPS DEGLWDTFVR HLPPSSTSHT VSLERLRHGV SYQFRVLAVN
EHGYGEPSAP SAAMSAQMDT PFYEEWWFLI ILALSGLILL LMIVFGLVLH GQNKKYKSCG
TGKAVSTVEE RVTLDNGGFT ALELNSRPVH VKSSFLRKNG TRSPPRPNPA GLRYSDEDIC
NNYNGAVSTD STALTERAAE LSESEATDSE CEDEPIKHSF VNHYMSDPSY FNSWKRQQKG
LKETLACAYE ECASGDGEGY YQTVVTQHSM GGVYTPTGQP APGSRTPLTG FSSFV
//
