ID W5UAT4_ICTPU Unreviewed; 544 AA.
AC W5UAT4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=MAGUK p55 subfamily member 2 {ECO:0000313|EMBL:AHH38975.1, ECO:0000313|RefSeq:XP_017342935.1};
GN Name=Mpp2 {ECO:0000313|EMBL:AHH38975.1};
GN Synonyms=mpp2a {ECO:0000313|RefSeq:XP_017342935.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH38975.1};
RN [1] {ECO:0000313|EMBL:AHH38975.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH38975.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017342935.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017342935.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
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DR EMBL; JT410231; AHH38975.1; -; mRNA.
DR RefSeq; XP_017342935.1; XM_017487446.3.
DR STRING; 7998.ENSIPUP00000015475; -.
DR Ensembl; ENSIPUT00000016135; ENSIPUP00000015475; ENSIPUG00000010516.
DR GeneID; 108276091; -.
DR KEGG; ipu:108276091; -.
DR CTD; 562207; -.
DR OMA; ICERENN; -.
DR OrthoDB; 2873706at2759; -.
DR Proteomes; UP000221080; Chromosome 2.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.287.650; L27 domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR014775; L27_C.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122:SF68; MEMBRANE PROTEIN, PALMITOYLATED 2A (MAGUK P55 SUBFAMILY MEMBER 2); 1.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF02828; L27; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00569; L27; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF101288; L27 domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 53..111
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 133..212
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 218..286
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 342..529
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 104..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 60393 MW; E41715664EB6B676 CRC64;
MPVAAARTEP ALSQVDVLSD STSSATANDL DLIFLKGIME SPVNAESPEE PRLEAVGDKN
MELLQDILRD LSPITHRSNT AAELSNILTQ PHFQSLLETH DSVASKTCET PPPSPQASVE
PNLPPVPADA VRMVGIRKVS GEHLGVTFRI ENGELVIARI LHGGMIDQQG LLHVGDIIKE
VNGQDVGEDP RVLQEMLQEA SGSIVLKVLP SYQEPHPPRQ VFVKCHFDYD PANDNLIPCK
EAGLQFSSGD VLQIVNQEDV NWWQARRVQG GSAGLIPSQL LEEKRKAFVK RDVELPPAGT
LCSGIGGKKK KKMMYLTTKN ADFDMHELMI YEEVARVPPF KRKTLVLIGA HGVGRRSLKN
KLLVSDPQLF GTTIPYTSRK PKSDERENRM YAFTTRSKME ADIKAGRYLE HGEYDGNLYG
TKIDSIHEVA EAGRLCILDV HPQALKILRT SEFLPYVVFI DAPEFEVLKS MNRAGIEAGV
VSKELTDAEL NRILDESWRI KRAYGHYFDL SVVNDSLDGT YSSLKDALKK LSGVQQWVPV
SWVF
//
