ID W5UEY3_ICTPU Unreviewed; 755 AA.
AC W5UEY3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Kin of IRRE-like protein 1 {ECO:0000313|EMBL:AHH40576.1};
DE SubName: Full=Kirre like nephrin family adhesion molecule 3, like {ECO:0000313|RefSeq:XP_017346782.1};
GN Name=Kirrel {ECO:0000313|EMBL:AHH40576.1};
GN Synonyms=kirrel3l {ECO:0000313|RefSeq:XP_017346782.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH40576.1};
RN [1] {ECO:0000313|EMBL:AHH40576.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH40576.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017346782.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017346782.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; JT414310; AHH40576.1; -; mRNA.
DR RefSeq; XP_017346782.1; XM_017491293.3.
DR STRING; 7998.ENSIPUP00000027480; -.
DR Ensembl; ENSIPUT00000028598; ENSIPUP00000027480; ENSIPUG00000018590.
DR GeneID; 108278115; -.
DR KEGG; ipu:108278115; -.
DR CTD; 557315; -.
DR OMA; TRIYDFS; -.
DR OrthoDB; 5362512at2759; -.
DR Proteomes; UP000221080; Chromosome 17.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0007420; P:brain development; IEA:Ensembl.
DR GO; GO:0032836; P:glomerular basement membrane development; IEA:Ensembl.
DR GO; GO:0007520; P:myoblast fusion; IEA:Ensembl.
DR GO; GO:0072015; P:podocyte development; IEA:Ensembl.
DR GO; GO:0039022; P:pronephric duct development; IEA:Ensembl.
DR GO; GO:0039021; P:pronephric glomerulus development; IEA:Ensembl.
DR CDD; cd05759; IgI_2_KIRREL3-like; 1.
DR CDD; cd05758; IgI_5_KIRREL3-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11640:SF51; KIN OF IRRE-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..755
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013540200"
FT TRANSMEM 489..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..101
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 109..215
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 220..296
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 305..385
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 389..485
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 541..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 617..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 718..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..560
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 82042 MW; C4B22451C8F0EF10 CRC64;
MLQFCIALIL LGTETEAAYF SQQPQDQVVV AGQSVTLPCV IVGYRGMVQW TKDGLALGGE
RDLPGWARYS LMGDPLSGEH SLVIESAELA DDAVYECQAT QAALRSHRAK LTVLVPPSDP
VVEGGPVVRL KAHAPHNLTC RASGAKPAAE ITWYRDGEVM LTAIYSKTLM EDGKRETAVS
LLPLVPDDRD SGRTYTCRVL NPAAPGGRQT SITINVQHPP SVTLSVQPQT VMEGAKVLFI
CSASASPEII GYRWSKGGVP IPEAKGDSLE VTVDYSYFTD PVSCEVFNSV GSTNVSTLVD
VQFGPRLLSE PKPQTVDTGM DAAFTCAWTG NPPLTLAWTK QGSSVVLSNS NTLHLKAVTQ
EDAGTYTCKA IVPRIGVSER DVTLTVNGPP IITAEATQQA VKHAKGKLEC LVGSSPPPDK
IVWTFGDVSL SSGSSGRFSV QTVNSDRGVL SSLVLSETLA QDFQLRYNCT AWNRFGTGTV
LVTLKEQEAL PLLIIIGSSV GGGCVFIVCV ITLASICCRH AAKGKKGTRL SKSDIRVQIV
HSDHNAARGN DDEEDVKEPM APNSSESPGT SRTEHSDLLE EEDDERSDIK DPTNGYYNVR
GHDDRHVART GFSEFVPTSR PVYTPCQLPS PGPLYSQNTT QPRVYDFSNR YATTPATRTT
YEQQPQQQQQ QQQQQQPQPQ QQTTPTMYPQ DPLYLPNTYS RAFTSYVKPA SFDKVDTFEQ
SDQAGKVSGS SRFSYASSQQ SDYGRPSQQR MQTHV
//
