ID W5UIN3_ICTPU Unreviewed; 291 AA.
AC W5UIN3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};
GN Name=ATP4B {ECO:0000313|EMBL:AHH39542.1};
GN Synonyms=LOC108259063 {ECO:0000313|RefSeq:XP_017313691.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH39542.1};
RN [1] {ECO:0000313|EMBL:AHH39542.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH39542.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017313691.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017313691.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: This is the non-catalytic component of the active enzyme,
CC which catalyzes the hydrolysis of ATP coupled with the exchange of
CC Na(+) and K(+) ions across the plasma membrane.
CC {ECO:0000256|RuleBase:RU362099}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the X(+)/potassium ATPases subunit beta family.
CC {ECO:0000256|ARBA:ARBA00005876, ECO:0000256|RuleBase:RU362099}.
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DR EMBL; JT411657; AHH39542.1; -; mRNA.
DR RefSeq; XP_017313691.1; XM_017458202.3.
DR STRING; 7998.ENSIPUP00000015480; -.
DR Ensembl; ENSIPUT00000016140; ENSIPUP00000015480; ENSIPUG00000010519.
DR GeneID; 108259063; -.
DR KEGG; ipu:108259063; -.
DR OMA; TAPRVNC; -.
DR OrthoDB; 2880589at2759; -.
DR Proteomes; UP000221080; Chromosome 26.
DR GO; GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1660; Na, k-atpase alpha subunit; 1.
DR InterPro; IPR000402; Na/K_ATPase_sub_beta.
DR InterPro; IPR038702; Na/K_ATPase_sub_beta_sf.
DR NCBIfam; TIGR01107; Na_K_ATPase_bet; 1.
DR PANTHER; PTHR11523:SF11; POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA; 1.
DR PANTHER; PTHR11523; SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT; 1.
DR Pfam; PF00287; Na_K-ATPase; 1.
DR PROSITE; PS00390; ATPASE_NA_K_BETA_1; 1.
PE 2: Evidence at transcript level;
KW Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781};
KW Ion transport {ECO:0000256|RuleBase:RU362099};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362099};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362099};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362099}; Transport {ECO:0000256|RuleBase:RU362099}.
FT TRANSMEM 37..63
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362099"
SQ SEQUENCE 291 AA; 33687 MW; 628E2A9EC908E2A1 CRC64;
MATLKEKRTC GQRCEDFGHF VWNSDEGKFM GRTPIRWLYI SLYYVAFYVV MTALFSLAIY
VLMYTLDPYK PDYQDRLKSP GVMVWPDTYN DEELEITYNM SDKNNWMTKS KILQDFLEPY
NDTIQAQCNH YNCTSGKYFI QHAFDAPKHT KWSCPFYQSM LGNCSGIDDP TFGYNTAQPC
VIIKMNRIIN FLPNNGTGSA PYVNCTALEG QDNVRGYTYY PTNGTLDLSY FPYYGKLAQP
TYMNPLVAVK LDLVNQRHAV IQCRVMANNI AHQNYYDPYE GKVIFHLTAL S
//
