ID W5UJY9_ICTPU Unreviewed; 175 AA.
AC W5UJY9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Troponin I, fast skeletal muscle {ECO:0000313|EMBL:AHH42326.1, ECO:0000313|RefSeq:XP_017341525.1};
GN Name=TNNI2 {ECO:0000313|EMBL:AHH42326.1};
GN Synonyms=LOC108275298 {ECO:0000313|RefSeq:XP_017341525.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH42326.1};
RN [1] {ECO:0000313|EMBL:AHH42326.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH42326.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017341525.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017341525.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin
CC filament regulatory complex which confers calcium-sensitivity to
CC striated muscle actomyosin ATPase activity.
CC {ECO:0000256|ARBA:ARBA00001988}.
CC -!- SIMILARITY: Belongs to the troponin I family.
CC {ECO:0000256|ARBA:ARBA00009930}.
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DR EMBL; JT417278; AHH42326.1; -; mRNA.
DR RefSeq; XP_017341525.1; XM_017486036.3.
DR STRING; 7998.ENSIPUP00000006481; -.
DR Ensembl; ENSIPUT00000006769; ENSIPUP00000006481; ENSIPUG00000004491.
DR GeneID; 108275298; -.
DR KEGG; ipu:108275298; -.
DR OMA; NAYMEET; -.
DR OrthoDB; 2882372at2759; -.
DR Proteomes; UP000221080; Chromosome 14.
DR GO; GO:0005861; C:troponin complex; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.350; -; 1.
DR Gene3D; 6.10.250.180; -; 1.
DR InterPro; IPR001978; Troponin.
DR InterPro; IPR038077; Troponin_sf.
DR PANTHER; PTHR13738; TROPONIN I; 1.
DR PANTHER; PTHR13738:SF31; TROPONIN I TYPE 2B (SKELETAL, FAST), TANDEM DUPLICATE 2-RELATED; 1.
DR Pfam; PF00992; Troponin; 1.
DR SUPFAM; SSF90250; Troponin coil-coiled subunits; 1.
PE 2: Evidence at transcript level;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179}.
FT REGION 144..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 54..102
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 175 AA; 19745 MW; 60DC475A5DC7ADD8 CRC64;
MSDKKMSSSR KHHLKSLMLS IAKGLIEAEA IEAVATRNAY MEETCPPLSL SGSVADLQEL
CKKLHSKIDK IDEERYDLAS KVSKSDKEID DLKIKVQDLQ GKFKKPALKK VRMSADSMLQ
ALLGSKHKVN MDLRANLKQV KKEVKEEPAE QVGDWRKNIE DKAGMDGRKK MFETS
//
