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Database: UniProt
Entry: W5UK36_ICTPU
LinkDB: W5UK36_ICTPU
Original site: W5UK36_ICTPU 
ID   W5UK36_ICTPU            Unreviewed;       451 AA.
AC   W5UK36;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   31-JUL-2019, entry version 30.
DE   SubName: Full=Friend leukemia integration 1 transcription factor {ECO:0000313|EMBL:AHH42529.1};
DE   SubName: Full=Friend leukemia integration 1 transcription factor isoform X2 {ECO:0000313|RefSeq:XP_017321485.1};
GN   Name=FLI1 {ECO:0000313|EMBL:AHH42529.1};
GN   Synonyms=fli1 {ECO:0000313|RefSeq:XP_017321485.1};
OS   Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC   Ictaluridae; Ictalurus.
OX   NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH42529.1};
RN   [1] {ECO:0000313|EMBL:AHH42529.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Mixed {ECO:0000313|EMBL:AHH42529.1};
RX   PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA   Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA   Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA   Peatman E., Liu Z.;
RT   "Efficient assembly and annotation of the transcriptome of catfish by
RT   RNA-Seq analysis of a doubled haploid homozygote.";
RL   BMC Genomics 13:595-595(2012).
RN   [2] {ECO:0000313|RefSeq:XP_017321485.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_017321485.1};
RG   RefSeq;
RL   Submitted (NOV-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; JT417867; AHH42529.1; -; mRNA.
DR   RefSeq; XP_017321485.1; XM_017465996.1.
DR   GeneID; 108264452; -.
DR   CTD; 2313; -.
DR   OrthoDB; 1113327at2759; -.
DR   Proteomes; UP000221080; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd08541; SAM_PNT-FLI-1; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR035575; Fli-1.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR035573; SAM_PNT-FLI-1.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF161; PTHR11849:SF161; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000221080};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000221080}.
FT   DOMAIN      111    197       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      280    360       ETS. {ECO:0000259|PROSITE:PS50061}.
FT   REGION       29     53       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      198    263       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     32     53       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    226    263       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   451 AA;  50666 MW;  CD03AF2FDD2AB24D CRC64;
     MDGTIKEALS VVSEDQSLFE PPYAAAAPLP KTDMTASSTQ DYGQQHKINP IPPQQEWINQ
     PGRINVKREY DHLNGTRESP VDCSVGKCNK LVSSSDTSQM GYGGYMDEKS APPPNMTTNE
     RRVIVPADPS LWSPDHVRQW LDWAVKEYGL LEIDTAMFQN TDGKELCKMS KEDFLRLTTV
     YNAEVLLSHL NYLRESSSSL SYNTPSHTDQ SPRLAAKEDA SYDAVRRTGW SNNMHSGKGS
     PTVVSQNVSK STEQTRPQPD PYQILGPTSS RLANPGSGQI QLWQFLLELL SDSANAGCIT
     WEGTNGEFKM TDPDEVARRW GERKSKPNMN YDKLSRALRY YYDKNIMTKV HGKRYAYKFD
     FHGIAQALQP HPTEPSMYKY PSDLAYVPPY HAHQQKVNFV SPHPPSMPVT SSNFFGPSNP
     YWSSPTAGIY PSASVPRHPN SHMPSHLGSY Y
//
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