ID W5UKU6_ICTPU Unreviewed; 158 AA.
AC W5UKU6;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Prefoldin subunit 2 {ECO:0000313|EMBL:AHH40262.1, ECO:0000313|RefSeq:XP_017328485.1};
GN Name=PFDN2 {ECO:0000313|EMBL:AHH40262.1};
GN Synonyms=pfdn2 {ECO:0000313|RefSeq:XP_017328485.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH40262.1};
RN [1] {ECO:0000313|EMBL:AHH40262.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH40262.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017328485.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017328485.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and
CC transfers target proteins to it. Binds to nascent polypeptide chain and
CC promotes folding in an environment in which there are many competing
CC pathways for nonnative proteins. {ECO:0000256|ARBA:ARBA00024667}.
CC -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC {ECO:0000256|ARBA:ARBA00008045}.
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DR EMBL; JT413479; AHH40262.1; -; mRNA.
DR RefSeq; XP_017328485.1; XM_017472996.3.
DR STRING; 7998.ENSIPUP00000012798; -.
DR Ensembl; ENSIPUT00000013333; ENSIPUP00000012798; ENSIPUG00000008711.
DR GeneID; 108268184; -.
DR KEGG; ipu:108268184; -.
DR CTD; 5202; -.
DR OMA; CFKMIGG; -.
DR OrthoDB; 178677at2759; -.
DR Proteomes; UP000221080; Chromosome 7.
DR GO; GO:0016272; C:prefoldin complex; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR Gene3D; 1.10.287.370; -; 1.
DR InterPro; IPR027235; PFD2.
DR InterPro; IPR002777; PFD_beta-like.
DR InterPro; IPR009053; Prefoldin.
DR PANTHER; PTHR13303; PREFOLDIN SUBUNIT 2; 1.
DR PANTHER; PTHR13303:SF0; PREFOLDIN SUBUNIT 2; 1.
DR Pfam; PF01920; Prefoldin_2; 1.
DR SUPFAM; SSF46579; Prefoldin; 1.
PE 2: Evidence at transcript level;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186}.
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 127..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 158 AA; 17130 MW; A5636330F7159A73 CRC64;
MAANSNSGTG SKSSGGKQSG PSAEQVVATF QRMRQEQRSM ASKAAELDME INEHSLVIDT
LKEVDPSRKC YRLVGGVLVE RTVKEVLPAL ENNKEQISKL VVSLNTQMQT KGRELTEYRE
RYNIRLVGED DKQGKGNAAQ AKESEEGGSK SGAGVLVS
//
