ID W5URK4_ICTPU Unreviewed; 689 AA.
AC W5URK4;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|EMBL:AHH42248.1};
DE SubName: Full=Protein MTSS 1 isoform X3 {ECO:0000313|RefSeq:XP_017320239.1};
GN Name=MTSS1 {ECO:0000313|EMBL:AHH42248.1};
GN Synonyms=LOC108263690 {ECO:0000313|RefSeq:XP_017320239.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHH42248.1};
RN [1] {ECO:0000313|EMBL:AHH42248.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH42248.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [2] {ECO:0000313|RefSeq:XP_017320239.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017320239.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JT417071; AHH42248.1; -; mRNA.
DR RefSeq; XP_017320239.1; XM_017464750.3.
DR Ensembl; ENSIPUT00000000089; ENSIPUP00000000063; ENSIPUG00000000073.
DR GeneID; 108263690; -.
DR OrthoDB; 3875239at2759; -.
DR Proteomes; UP000221080; Chromosome 1.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR CDD; cd07643; I-BAR_IMD_MIM; 1.
DR CDD; cd22060; WH2_MTSS1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR013606; I-BAR_dom.
DR InterPro; IPR030127; MTSS1/MTSS2.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR Pfam; PF08397; IMD; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51338; IMD; 1.
DR PROSITE; PS51082; WH2; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 1..250
FT /note="IMD"
FT /evidence="ECO:0000259|PROSITE:PS51338"
FT DOMAIN 661..678
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 138..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 255..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 437..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 614..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..388
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..462
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..664
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 689 AA; 75763 MW; 19DBD92355D5C676 CRC64;
MEVVMEKECS ALGGLFQAII NDMKSSYPVW DDFISKAGKL QSQLRTTVMA MAAFLDAFQK
VADLATGTRG GTRDIGSALT RMCMRHRSIE AKLKQFSTTF IDCLINPLQE QLEEWKKGAN
TLDKDHAKEY KKARQEIKKK SSDTLKLQKK AKKGRGDIQP QLHSAVQDVT DKYLLLEETE
KQAVRKALIE ERARFCIFVS MLRPVVDEEV AMLGEIVHLQ TIAEDLKVLT VDPHKLPPAS
EQIIHDLKGS DYSWSYQTPP SSPSTTMSRK SSMCSSLNSV NSSDSRSSGS LSHSSSPLYR
YRSITVPQQV PARLASVSSH DSGFASHDAF QSKSPSPMPS DPTSQLSNGY DHYGPAEASY
PPGVAFPFPP NPSSSSSSSS STPRSWSRPG SALMPDYPHY STLTPGMLPP SSKIPSWKDW
AKPGPYDQPM VNTLRRRKEP KEAVDSNGAY QPTLNSTQPE DLHQKTRNIA NSPNEVEVQQ
DLALALSRGL QLEAQCSSRD SLQCSSGYST QSTTPCCSED TIPSQVSDYD YFSEQQDFDK
SSTVPRNSDL GQSYRKLFQA KRPASTAGIP SVPGVATIRR TPSTKPSVRR GTGPFAIQTP
VIPVMTPTVP DFTGVEPNEE AEPGDDAEPE PVLPVQSWSG QASINPPLHA TYEEHEDAVE
EGDTMLQSIR RGVRLKKTST NDRSAPRIP
//
