ID   W5WDY8_9PSEU            Unreviewed;       908 AA.
AC   W5WDY8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN   ORFNames=KALB_5618 {ECO:0000313|EMBL:AHH98980.1};
OS   Kutzneria albida DSM 43870.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Kutzneria.
OX   NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHH98980.1, ECO:0000313|Proteomes:UP000019225};
RN   [1] {ECO:0000313|EMBL:AHH98980.1, ECO:0000313|Proteomes:UP000019225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43870 {ECO:0000313|EMBL:AHH98980.1};
RX   PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA   Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA   Bechthold A., Kalinowski J., Luzhetskyy A.;
RT   "Complete genome sequence of producer of the glycopeptide antibiotic
RT   Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT   of Pseudonocardiaceae.";
RL   BMC Genomics 15:885-885(2014).
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DR   EMBL; CP007155; AHH98980.1; -; Genomic_DNA.
DR   RefSeq; WP_025358920.1; NZ_CP007155.1.
DR   AlphaFoldDB; W5WDY8; -.
DR   STRING; 1449976.KALB_5618; -.
DR   KEGG; kal:KALB_5618; -.
DR   PATRIC; fig|1449976.3.peg.5636; -.
DR   eggNOG; COG2197; Bacteria.
DR   HOGENOM; CLU_006850_4_1_11; -.
DR   OrthoDB; 3656034at2; -.
DR   Proteomes; UP000019225; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019225}.
FT   DOMAIN          843..908
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   REGION          831..850
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   908 AA;  96128 MW;  C023B430CB50CFA4 CRC64;
     MPLFGRETEL KSLTELVDGP EECGGILLTG EPGIGKSALV AEAVSAASVA GLRVLTTTGV
     EAEQNLAYAG LHQLLYPVRA GVDALPAPQK AALRTALGLA DGAEPSAYLV GLAALTLLAE
     QAVDRPLLLV AEDVHWLDRA SVDVLAFVAR RIESEPVALL ATLREGERSP LQDAGLSPMP
     VARLSTEDAA GFLDSVAPGL AAPVRQQVLT EAAGNPLALA ELPAALSGPA QLDRAQLDPV
     LPLSDRLERA FTARVVGLPA PTRTALLVAA LSQTGSVAET LAATGPLLGG TVEVEVLAPA
     VEAGLVEVAT GSVTFRHPLT RSAIPAAATL AERRQAHLAL AETLAGQPDR RAWHQAAATT
     SADEAVAGEL EQAAERARRR GGTTAAIAAL EQAARLSERQ DRRGDRLLRA AELATECGRR
     DLTERLVREA QALDLTPRQR AAAAWLLSGF EDGVREDIAR VAELGELAAS VAGDGHTEVA
     ARILWSTAMR CFWSEPGART RRALLAVSDR LPLPDEDPRK VAIAAYVAPF ERGETVLAGL
     RTLARSAGEN PEVDRYLGSA ALQVGAFDLA ARFAAAAVPG LRAQGLLGVL PRALAVQAWS
     RTRLGDLATA VPIAAEAARL AKETHQPFMF GLAKAVQAEI AALRGDHKQA TALADEAERA
     GLAAGARPVL ATVQLTRGLT ALSEGRYEDA FADLRRMLDP ADPAYQLALR AYCLAELTEA
     AVRSGQTETM REILAEMEPL GTTTSSPALH IGLRYARAVL ASTGDAEELF LAALRADLTG
     WPAERGRVHL AFGEWLRRQR RVVESRTHLR TARETFDALG MTAWGERARR ELRGAGESSP
     NRGPDAREKL TPHELSVAQL AAEGLTNREI GQRLYLSHRT VGTHLHRIFP KLGISSRADL
     AGVLSKLE
//