ID   W5WEU8_9PSEU            Unreviewed;      1308 AA.
AC   W5WEU8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=ATP-dependent RNA helicase HrpA {ECO:0008006|Google:ProtNLM};
GN   ORFNames=KALB_6368 {ECO:0000313|EMBL:AHH99728.1};
OS   Kutzneria albida DSM 43870.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Kutzneria.
OX   NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHH99728.1, ECO:0000313|Proteomes:UP000019225};
RN   [1] {ECO:0000313|EMBL:AHH99728.1, ECO:0000313|Proteomes:UP000019225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43870 {ECO:0000313|EMBL:AHH99728.1};
RX   PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA   Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA   Bechthold A., Kalinowski J., Luzhetskyy A.;
RT   "Complete genome sequence of producer of the glycopeptide antibiotic
RT   Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT   of Pseudonocardiaceae.";
RL   BMC Genomics 15:885-885(2014).
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DR   EMBL; CP007155; AHH99728.1; -; Genomic_DNA.
DR   RefSeq; WP_030108496.1; NZ_CP007155.1.
DR   STRING; 1449976.KALB_6368; -.
DR   KEGG; kal:KALB_6368; -.
DR   PATRIC; fig|1449976.3.peg.6390; -.
DR   eggNOG; COG1643; Bacteria.
DR   HOGENOM; CLU_001832_3_3_11; -.
DR   OrthoDB; 9805617at2; -.
DR   Proteomes; UP000019225; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd17989; DEXHc_HrpA; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019225}.
FT   DOMAIN          88..251
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          281..448
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1308 AA;  146724 MW;  B597FE2DC93F54FA CRC64;
     MGPSPVSSTL AELRDRLPQL MLRDERRLRR RLDGLAKKPE GPERALELAA LSAEVDAAVL
     RVADRALTVP AIDYPPQLPV SEHRDRIAEL IREHQVVIVA GETGSGKTTQ LPKICLELGR
     GLRGMIGHTQ PRRIAARTVA ERIAEELHTE LGQAVGYKVR FTDQVGGRSL VKLMTDGILL
     AEIQNDRMLS QYDTLIIDEA HERSLNIDFL LGYLHQLLPR RPELKVIITS ATIDPQRFSR
     HFRDAPVVEV SGRTYPVEVR YRPVIDPEDP ESDPDRDQVQ AICDAVDELC AEGPGDILVF
     LSGEREIRDT ADALSKQDLR NTEILPLYAR LSVGEQHKVF KPHTGRRVVL STNVAETSLT
     VPGIKYVVDP GNARISRYSH RLKVQRLPIE PISQASANQR KGRCGRVSEG ICIRLYSEED
     FLSRPEFTDA EILRTNLASV ILQMTAAGLG DIAAFPFIDP PDRRNIADGI GLLQELGAVG
     APDSSGQRKL TQVGRRLAQL PVDPRLARMV VEAERNGCTR EVMVIAAALS IQDPRERPTE
     QQQAAQQQHA RFTDPTSDFL SYLNLWNYLR EQQKALSSNQ FRKMCRAEFL NYLRVREWQD
     IYAQLRQVIK SQGVSLEGNE VDPQAIHLSL LAGLLSHLGF KDVSAKDAKK KGPTEYLGAR
     NARFAIFPGS ALSRSQPRWV MAAELVETSR LWARIVARIE PEWAEKLAPH LVRSTYSEPH
     WDAERGSVTA MEKVTLYGLP IVASRRVNYG RIDPGLCRDL FIRHALVDGE WTTHHQFWHA
     NRTLLREVDK LEDRARRRDI RVDDQALFDF YDKRIGAEVV SVRHFDTWWK KTRRDQPDLL
     TFDLDMLVND SAGEVSARDY PDHWDQGGVP LPLTYRFEPG TSTDGVTVRV PLPVLGQLDG
     DGFAWQIPGL RLELVTSLIK SLPKAVRRNF VPAPTFAKAV VDRITDQDIN LLEAVERELR
     TLSGVVVPRE AWQLDQVPEH LKTTFHVVDE SDRTLAKGKD LESIKQELLD TMRAALSASP
     NNIEREGLRE WDFGPLPRSH RQAVSGYEVT AYPALVDQGD TVAVRLLDTQ AQQRQSMLRG
     TRRLLLLNLP SPVKLVVRSL SNEAKLTLSR NPHGGVPALL EDCIAAAVDR IVAEGGGPAW
     DAEGFGKLLT RARTALGPTV LEVVDRVRRI LAAEQAVQAR LAAARFAPTE SVTDIRRQLK
     GLVCAGFATE TGWARLSDVE RYLRAVERRL EKLPENPARD VERTQQVAEI TAEYRELVGA
     LPPGEPVGEK LVAIRWMIEE LRVSYFAQTL GTAYPVSEKR IHKAMDEV
//