ID W5WKC2_9PSEU Unreviewed; 274 AA.
AC W5WKC2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=biotin--[biotin carboxyl-carrier protein] ligase {ECO:0000256|ARBA:ARBA00024227};
DE EC=6.3.4.15 {ECO:0000256|ARBA:ARBA00024227};
GN ORFNames=KALB_7960 {ECO:0000313|EMBL:AHI01318.1};
OS Kutzneria albida DSM 43870.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Kutzneria.
OX NCBI_TaxID=1449976 {ECO:0000313|EMBL:AHI01318.1, ECO:0000313|Proteomes:UP000019225};
RN [1] {ECO:0000313|EMBL:AHI01318.1, ECO:0000313|Proteomes:UP000019225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43870 {ECO:0000313|EMBL:AHI01318.1};
RX PubMed=25301375; DOI=10.1186/1471-2164-15-885;
RA Rebets Y., Tokovenko B., Lushchyk I., Ruckert C., Zaburannyi N.,
RA Bechthold A., Kalinowski J., Luzhetskyy A.;
RT "Complete genome sequence of producer of the glycopeptide antibiotic
RT Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus
RT of Pseudonocardiaceae.";
RL BMC Genomics 15:885-885(2014).
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DR EMBL; CP007155; AHI01318.1; -; Genomic_DNA.
DR RefSeq; WP_025361133.1; NZ_CP007155.1.
DR AlphaFoldDB; W5WKC2; -.
DR STRING; 1449976.KALB_7960; -.
DR KEGG; kal:KALB_7960; -.
DR PATRIC; fig|1449976.3.peg.7999; -.
DR eggNOG; COG0340; Bacteria.
DR HOGENOM; CLU_051096_5_0_11; -.
DR OrthoDB; 9807064at2; -.
DR Proteomes; UP000019225; Chromosome.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd16442; BPL; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR InterPro; IPR003142; BPL_C.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR InterPro; IPR008988; Transcriptional_repressor_C.
DR NCBIfam; TIGR00121; birA_ligase; 1.
DR PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR Pfam; PF02237; BPL_C; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR SUPFAM; SSF50037; C-terminal domain of transcriptional repressors; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
PE 4: Predicted;
KW Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Reference proteome {ECO:0000313|Proteomes:UP000019225}.
FT DOMAIN 32..147
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|Pfam:PF03099"
FT DOMAIN 221..268
FT /note="Biotin protein ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02237"
SQ SEQUENCE 274 AA; 28141 MW; 9F6F5CCA2EBB29AD CRC64;
MTQPLDLEAL RAALVAPGGP YAALDVVPST GSTNADLREA ANAGAEDRTV LIAEQQTAGQ
GRRARTWVSP AGSGIYLSVL LRPHEVPPNR LPGITLLAGV ALVSTVRAST GVDAVLKWPN
DLLAGPERAK CAGILAESIG GGAVVLGIGL NVAALPEGVP AGAGGLPPTS LEQQGASHTD
RTRLVVELLL ALAQLDARWR LAYGDPVACG LLDAYREHCA TLGLRVRVEL PGNSELLGTA
VDVDREGQLV IRSDGGGQRA VHAGDVVHLR SVTG
//
