ID   W6A771_9MOLU            Unreviewed;       908 AA.
AC   W6A771;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=DEAD/DEAH family helicase {ECO:0000313|EMBL:AHI52842.1};
GN   ORFNames=SCULI_v1c05010 {ECO:0000313|EMBL:AHI52842.1};
OS   Spiroplasma culicicola AES-1.
OC   Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC   Spiroplasma.
OX   NCBI_TaxID=1276246 {ECO:0000313|EMBL:AHI52842.1, ECO:0000313|Proteomes:UP000019267};
RN   [1] {ECO:0000313|EMBL:AHI52842.1, ECO:0000313|Proteomes:UP000019267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AES-1 {ECO:0000313|EMBL:AHI52842.1};
RX   PubMed=24534435;
RA   Chang T.H., Lo W.S., Ku C., Chen L.L., Kuo C.H.;
RT   "Molecular evolution of the substrate utilization strategies and putative
RT   virulence factors in mosquito-associated Spiroplasma species.";
RL   Genome Biol. Evol. 6:500-509(2014).
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DR   EMBL; CP006681; AHI52842.1; -; Genomic_DNA.
DR   RefSeq; WP_025363078.1; NZ_CP006681.1.
DR   AlphaFoldDB; W6A771; -.
DR   STRING; 1276246.SCULI_v1c05010; -.
DR   KEGG; scq:SCULI_v1c05010; -.
DR   PATRIC; fig|1276246.3.peg.499; -.
DR   eggNOG; COG1061; Bacteria.
DR   eggNOG; COG3886; Bacteria.
DR   HOGENOM; CLU_005588_1_1_14; -.
DR   OrthoDB; 9802848at2; -.
DR   Proteomes; UP000019267; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR025202; PLD-like_dom.
DR   PANTHER; PTHR47396:SF1; ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR   PANTHER; PTHR47396; TYPE I RESTRICTION ENZYME ECOKI R PROTEIN; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF13091; PLDc_2; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:AHI52842.1};
KW   Helicase {ECO:0000313|EMBL:AHI52842.1};
KW   Hydrolase {ECO:0000313|EMBL:AHI52842.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:AHI52842.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019267}.
FT   DOMAIN          219..374
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          429..586
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   908 AA;  107237 MW;  722D641C8E136332 CRC64;
     MKEEKFFTNK DQQELLTEIQ NEIKTSDEVY LIYPFISKMI LNKISSTFDY CLEHNIPIKI
     ISTTFDDLSQ FNNLNELKNI VEKYSNIEIK IEDNLEKHSE RIHIKASIFK RKHKPDSAII
     GSSNLTYKGM VSGREWNIKI ISKQENDLVQ QMIEEFDNLW VEDFINFSDT EQREFLIQRV
     KENQEAKIQL DLMNQNSNFV YVRRYLYKFQ KEVINKLSYR RFMGKDKHLV VMATGTGKTL
     VSAFDYKRQI ESAKQNLRIL FLAHQKEIID QAIKTYRQVL NDPNFGEVLY DGQNISQKPK
     HLFATIQSLS NKISDFEKDQ FDIIVFDEAH HIAANTFDKT FNYFQPKQIL GLTATPERED
     GKDIKTYFNN EFASELRLWD AVNQKLLCPF DYYCVDDTST DLTGVDLDSD KEIFKKINTD
     SRNELLYKTI EKYLGIYARP TALIFCVTIE HANIIASFLK LKNLKAEVLT SENKKERKRI
     LHEFSTGRIN YLCVVNIFNE GIDIPQINTI ILLRPTNSKT IYLQQLGRGL RKTELKNKLE
     VYDLISNIDS KYDLTLGIRN LFDPKIIGTN FISAKQGLPY NSTITLEKRA EELILRSLKK
     WYGNKIILKD QVVKYYKKYQ DKALEMIIKD YDLSLQDFYN TLDDLFLKTA KQIGKYQKFE
     NETKRNKNIL KQFIFLDNYQ IINYFLKRLS NQILKSEIDL DFDNLLMTSF LYEITSMDKF
     LQLYPNYLEI NDLVEHFINN NKIIVEELIL ILKYKLENET LIFTSNIDKL LSIDSTYTVK
     QSLAAVGRTN FLHYREELKV LTFQAGYLTW QNSKQIILAD EDGTGYGKLT KYDPDNKKFY
     WSLPETMTLK HKIIKDFKDE NIIKYLFIHD RQNYEQKNMF LKLYKFTGIG TFKEMLVNNY
     LTAEFDIF
//