ID W6AB34_9MOLU Unreviewed; 875 AA.
AC W6AB34;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:AHI54247.1};
GN ORFNames=SSABA_v1c08480 {ECO:0000313|EMBL:AHI54247.1};
OS Spiroplasma sabaudiense Ar-1343.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC Spiroplasma.
OX NCBI_TaxID=1276257 {ECO:0000313|EMBL:AHI54247.1, ECO:0000313|Proteomes:UP000019265};
RN [1] {ECO:0000313|EMBL:AHI54247.1, ECO:0000313|Proteomes:UP000019265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ar-1343 {ECO:0000313|EMBL:AHI54247.1};
RX PubMed=24534435;
RA Chang T.H., Lo W.S., Ku C., Chen L.L., Kuo C.H.;
RT "Molecular evolution of the substrate utilization strategies and putative
RT virulence factors in mosquito-associated Spiroplasma species.";
RL Genome Biol. Evol. 6:500-509(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
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DR EMBL; CP006934; AHI54247.1; -; Genomic_DNA.
DR RefSeq; WP_025251383.1; NZ_CP006934.1.
DR AlphaFoldDB; W6AB34; -.
DR STRING; 1276257.SSABA_v1c08480; -.
DR KEGG; ssab:SSABA_v1c08480; -.
DR PATRIC; fig|1276257.3.peg.860; -.
DR eggNOG; COG0383; Bacteria.
DR HOGENOM; CLU_003442_2_1_14; -.
DR OrthoDB; 9772207at2; -.
DR Proteomes; UP000019265; Chromosome.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2220; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF2; MANNOSYLGLYCERATE HYDROLASE; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019265}.
FT DOMAIN 289..367
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 875 AA; 101756 MW; 91E66C61B8AFEB66 CRC64;
MKKIRIHIVP HAHWDKEWYF TKQDSDLLLN GNLEKLNKAI KSNENFKNFT YDGQSSIIDD
FKIFNGNENE LATNIKNNKI ILGPWYSQPD LFNTTSEAIV RNLLIGTNMA ESFGSSMRNA
YVPDSFGQSS QMPQIYKLAE LDNMIYWRGI TKEKMQNSVL HYWEGLDGTK IKSYNFLKGY
WIMGSFFPYL ELNQNNAADY AKKFSKDFGK TLGELKKFNP HSPNNLLLPL GGDQAPVNEY
IDIFLAELNK IDNEHDWYWS SYDEYFEAIE NITEIPTVKG ELKSPENSRI HKTIGSQRVD
IKQLAKEVDN LIFEQLEPLA VYFEQIGGAY PKEIINKILK SALISHAHDS LGGCNTDATN
KDVIARLNWA KQWAQSQITK IFKSITNNSK VNELILFNPN PKKIKTDMEM TIFTKTQDFE
ISCGTKKIEK IILENTFINP NLEINTGTNG ESQEAINGYW KTKILLLESK FEGLQAKKLF
IKELNNKVVN VDWKNKNTWE NQKWKITITT DGEINLFDKI KNINFEKQMV LQAQRDMGDS
YDFSPETIEN FIINDLINSK SKIKEFDKHC EIIIENNYSI KNGKDQKILI KIFISQENLI
NFKVTINNKN ENIKWRILFD SQIYDSQFSF ANQAYGVEKR PVVLKENEFW NEKGWNEKPI
EIETNESFVY LKNDVYQFGL ITRGTNEYQI IGKQFNIIAL TLFRSVSLLG RNNLLWRPGR
ASGTSDYLIE TEDSKLLKEI NFEFDLFVEN ISNSVWNLAQ NKLAKPIYYQ KQNLNLYSNR
FERFLISDLG DIREIELANL LTIENQNLIV KAIKKHESKN QIILRIFNSS DKKEALQTKG
AFKIKEEVNL LERKNCKPNL VFKSYEIKTF IIDRG
//
