ID W6AB97_9MOLU Unreviewed; 513 AA.
AC W6AB97;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=PTS system mannitol-specific IIBC component {ECO:0000313|EMBL:AHI54261.1};
GN Name=mtlA2 {ECO:0000313|EMBL:AHI54261.1};
GN ORFNames=SSABA_v1c08620 {ECO:0000313|EMBL:AHI54261.1};
OS Spiroplasma sabaudiense Ar-1343.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC Spiroplasma.
OX NCBI_TaxID=1276257 {ECO:0000313|EMBL:AHI54261.1, ECO:0000313|Proteomes:UP000019265};
RN [1] {ECO:0000313|EMBL:AHI54261.1, ECO:0000313|Proteomes:UP000019265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ar-1343 {ECO:0000313|EMBL:AHI54261.1};
RX PubMed=24534435;
RA Chang T.H., Lo W.S., Ku C., Chen L.L., Kuo C.H.;
RT "Molecular evolution of the substrate utilization strategies and putative
RT virulence factors in mosquito-associated Spiroplasma species.";
RL Genome Biol. Evol. 6:500-509(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP006934; AHI54261.1; -; Genomic_DNA.
DR RefSeq; WP_025251397.1; NZ_CP006934.1.
DR AlphaFoldDB; W6AB97; -.
DR STRING; 1276257.SSABA_v1c08620; -.
DR KEGG; ssab:SSABA_v1c08620; -.
DR PATRIC; fig|1276257.3.peg.874; -.
DR eggNOG; COG2213; Bacteria.
DR HOGENOM; CLU_028721_2_0_14; -.
DR OrthoDB; 9814222at2; -.
DR Proteomes; UP000019265; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022872; F:protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR CDD; cd05567; PTS_IIB_mannitol; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR036095; PTS_EIIB-like_sf.
DR InterPro; IPR003501; PTS_EIIB_2/3.
DR InterPro; IPR029503; PTS_EIIB_mannitol.
DR InterPro; IPR013014; PTS_EIIC_2.
DR Pfam; PF02302; PTS_IIB; 1.
DR SUPFAM; SSF52794; PTS system IIB component-like; 1.
DR PROSITE; PS51104; PTS_EIIC_TYPE_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000019265};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 38..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..378
FT /note="PTS EIIC type-2"
FT /evidence="ECO:0000259|PROSITE:PS51104"
SQ SEQUENCE 513 AA; 56010 MW; B99F1AA36FF77524 CRC64;
MKEVIKELDS KLSSKERHKL FWKRNFDKQT IVRRIQKFGG WLSSMIMPMI GIMIAWGLLT
AFFIPTGWTP VAIINDYIIV NMMTYLLPTL IAFNAGKIVH GTRGGMVATL VVFGVIAGNQ
VNPGFIDGST PSPQFLAAMM VGPLAAGILK GFDKLVENRI KQGFEMLVNN FSLGILGAIM
CVGSFYGMPY VFNSISWAFA KAVEFLINNS MIFLAAIIIE PAKVLFLNNA INHGVLTPIG
TQLVAEHGKS VLFLLEANPG PGFGLLVAII LFDKKSRGNA AGASVIHLFG GIHEVYFPFV
LMRFEMLLAL IGGGIAGNAI FQIFNVGLIA PASPGSIIAI FIFAQSSGLN YLWLSVGILA
SSATAFGTAA LIFIINRKKY SKQGMIDLNL ATKKTLELKG KKSNVLKLQE EMKKPQLIIF
ACEAGMGSSA MGAGLLRKHL KAADLEIEVK NFPIKELPEN SEFVITQSAL TPLAMKKCPK
AIHRSISNFL DNNFYKNIIE EIQVVATKEK ELR
//
