ID W6K389_9MICO Unreviewed; 904 AA.
AC W6K389;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Glutamate-ammonia-ligase adenylyltransferase {ECO:0000313|EMBL:CCH72944.1};
DE EC=2.7.7.42 {ECO:0000313|EMBL:CCH72944.1};
GN Name=glnE {ECO:0000313|EMBL:CCH72944.1};
GN ORFNames=BN11_2140001 {ECO:0000313|EMBL:CCH72944.1};
OS Tetrasphaera australiensis Ben110.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Tetrasphaera.
OX NCBI_TaxID=1193182 {ECO:0000313|EMBL:CCH72944.1, ECO:0000313|Proteomes:UP000035763};
RN [1] {ECO:0000313|EMBL:CCH72944.1, ECO:0000313|Proteomes:UP000035763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ben110 {ECO:0000313|EMBL:CCH72944.1,
RC ECO:0000313|Proteomes:UP000035763};
RX PubMed=23178666; DOI=10.1038/ismej.2012.136;
RA Kristiansen R., Nguyen H.T.T., Saunders A.M., Nielsen J.L., Wimmer R.,
RA Le V.Q., McIlroy S.J., Petrovski S., Seviour R.J., Calteau A.,
RA Nielsen K.L., Nielsen P.H.;
RT "A metabolic model for members of the genus Tetrasphaera involved in
RT enhanced biological phosphorus removal.";
RL ISME J. 7:543-554(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH72944.1}.
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DR EMBL; CAJA01000129; CCH72944.1; -; Genomic_DNA.
DR AlphaFoldDB; W6K389; -.
DR STRING; 1193182.BN11_2140001; -.
DR Proteomes; UP000035763; Unassembled WGS sequence.
DR GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR Gene3D; 1.20.120.1510; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR023057; GlnE.
DR InterPro; IPR005190; GlnE_rpt_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR Pfam; PF08335; GlnD_UR_UTase; 2.
DR Pfam; PF03710; GlnE; 2.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000313|EMBL:CCH72944.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:CCH72944.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000035763};
KW Transferase {ECO:0000313|EMBL:CCH72944.1}.
FT DOMAIN 24..231
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 252..392
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
FT DOMAIN 497..733
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 757..896
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
SQ SEQUENCE 904 AA; 98800 MW; A5D9BAEE2B3C6943 CRC64;
MIGASIALGD HLVAHPEHWR SVAEARPRTP EQRVARIVGR VRNPDPGLSP DDALRVYYRR
GLLGISALDL VAPDPLVKLP DTAAALADLA AAALEGALVI AQSELPDDAA QCRFAVIAMG
KTGGRELNYI SDVDVIFVAE PADGVSEQDA MAAAARLATR LMTACSAATA HGTLWPVDAA
LRPEGKAGPL VRTVASHKQY YERWAKTWEF QALLKARPVA GDKEVGAAYL QAMAPMVWQA
ASRENFVDDV QAMRRRVEAH IPSAEADRQL KLGPGGLRDI EFSVQLLQLV HGRTDERIRS
GTTLDALAAL AAYGYVGRDD AAQLAAAYRL LRTLEHRIQL LRLRRTHLMP TSPHELRRLG
RALGHREDPA AAVVAEWKAE AREVRRLHER LFYRPLLGAV ARLGTDDARL TPEAARERLS
ALGFRDPTGA LRHLEALTEG LSRRAAIQRH LLPVMLGWFA AEADPDGGLL AFRKVSESLD
SSHWYLRLLR DEPAAAEQLA RTLARSKFAA EVLVAAPEAV QILGEPGGVR PHSRGDIERR
MRTAAQRKTS LDDAIAAARQ VRRLELFRIA VADLVGDLPQ PDVGRALSDL TAATIEVALQ
FVIREEEKRA GRPLVTDLLI VGMGRLGGNE LGYASDADVL FVHDPHIGAD EDAAQAQALA
VVKSMQRVLS VPGPDPAIGL DADLRPEGKN GPLVRSLDSY RAYYDRWALI WEAQALVRAR
PIAGNAELAA RFEDLIDPIR WHGAGLSAQD LREIRRLKAR MEAERLPRGA DKRTHFKLGT
GGLSDVEWVV QTLQMEHAHN YPTLRTTSTL PALTAATQAR LISSADSAAL AKAWEFAAHA
RNASMLYRGK AVESVPTDSR EADGTARIMG LPPGSGQEFG EDYRRITRHA RAVVDRVFYG
REES
//
