ID W6KP80_9TRYP Unreviewed; 767 AA.
AC W6KP80;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=EF-hand domain-containing family member C2 {ECO:0000256|ARBA:ARBA00039880};
GN ORFNames=GSEM1_T00001730001 {ECO:0000313|EMBL:CCW63359.1};
OS Phytomonas sp. EM1.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Phytomonas.
OX NCBI_TaxID=479712 {ECO:0000313|EMBL:CCW63359.1, ECO:0000313|Proteomes:UP000027080};
RN [1] {ECO:0000313|EMBL:CCW63359.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EM1 {ECO:0000313|EMBL:CCW63359.1};
RA Genoscope - CEA;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CCW63359.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EM1 {ECO:0000313|EMBL:CCW63359.1};
RX PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA Wincker P., Dollet M.;
RT "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL PLoS Genet. 10:e1004007-e1004007(2014).
CC -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC doublet microtubules (DMTs) in cilia axoneme, which is required for
CC motile cilia beating. {ECO:0000256|ARBA:ARBA00035003}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC {ECO:0000256|ARBA:ARBA00004430}.
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DR EMBL; HF955074; CCW63359.1; -; Genomic_DNA.
DR AlphaFoldDB; W6KP80; -.
DR EnsemblProtists; CCW63359; CCW63359; GSEM1_T00001730001.
DR OrthoDB; 124589at2759; -.
DR Proteomes; UP000027080; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 2.30.29.170; -; 3.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR006602; DM10_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12086:SF11; EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2; 1.
DR Pfam; PF06565; DM10_dom; 3.
DR SMART; SM00676; DM10; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS51336; DM10; 3.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000027080}.
FT DOMAIN 89..196
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 264..383
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
FT DOMAIN 443..547
FT /note="DM10"
FT /evidence="ECO:0000259|PROSITE:PS51336"
SQ SEQUENCE 767 AA; 88310 MW; AC08A6F22A132B7F CRC64;
MTKTFSHIPK DDNLPLSLGS NFHDDPINRN TLRKSHNLFL PQQENGAPHT EYHYGDLKIT
RDANTIQSDA EQEAWDGWGT EKFSNADYND FVVRLLAYFV ESITANSTEE KRVRKVCINF
FMHDNSISII ELKEANSGIA QGTILSRCQV PKKSDDDKEL VSLKDLKIGN EALIYGINYH
IIDMDRRSRR FFKEILHEDV PQPQDFPLTS ASYFSCFQKN NPGRTFTSDD MDRKCAIEPQ
FTETFSKRSK EDILISQQFF KNEINEHLSY LALWDDRGSI SGDLHFCVIK LFLENFAIEV
MEQRPENSNW SGGKVLISRQ RTPKPGSDIT KSKFQEHTFG KLMKNGYLEP QDLMIGETYI
MYGKPFFIYG CDQKTREYMK LNFNIDLGSN IDITPFTTEK KPEILFYPPP PNGFGSDWGQ
RDNWLTLCGK PPKQDLETMN SETGRVLIFA ARLANPLTKG DDKREFVIVF YCDTKELCIN
EKTQPNSGFT CGRFLAKGPH QKELANGTTA PFEASDFAIG KSITIYKRIF LLCEMTEGTK
RALEESDKLT TEDRIKDLIF LFKQQLKLKF MKAREAYLAL APQGIFGYKQ IKDFLRTCSC
NINDEEAIVM AQNLFPDDKN VLSFETFSQI FSEMSESMVG TSSASYSAQN INMSVKGSQK
ESILKSEGDY RCRQLRRFLK EKLTQRKGIL QQQFRLFSEY SLNSRLSREA FRRSLHSIIH
SGMEKMDEDM LVSMLFDGVE DDNNEITYTQ FQEFLNQGAS PRRGDCF
//
