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Database: UniProt
Entry: W6KRA4_9TRYP
LinkDB: W6KRA4_9TRYP
Original site: W6KRA4_9TRYP 
ID   W6KRA4_9TRYP            Unreviewed;       345 AA.
AC   W6KRA4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   11-DEC-2019, entry version 19.
DE   RecName: Full=Ribosomal RNA-processing protein 8 {ECO:0000256|RuleBase:RU365074};
DE            EC=2.1.1.- {ECO:0000256|RuleBase:RU365074};
DE   Flags: Fragment;
GN   ORFNames=GSEM1_T00000363001 {ECO:0000313|EMBL:CCW59816.1};
OS   Phytomonas sp. isolate EM1.
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Phytomonas;
OC   unclassified Phytomonas.
OX   NCBI_TaxID=134006 {ECO:0000313|EMBL:CCW59816.1, ECO:0000313|Proteomes:UP000027080};
RN   [1] {ECO:0000313|EMBL:CCW59816.1, ECO:0000313|Proteomes:UP000027080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EM1 {ECO:0000313|EMBL:CCW59816.1};
RX   PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA   Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA   Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA   Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA   Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA   Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA   Wincker P., Dollet M.;
RT   "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT   Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL   PLoS Genet. 10:e1004007-e1004007(2014).
CC   -!- FUNCTION: Probable methyltransferase required to silence rDNA.
CC       {ECO:0000256|RuleBase:RU365074}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|RuleBase:RU365074}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. RRP8 family.
CC       {ECO:0000256|RuleBase:RU365074}.
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DR   EMBL; HF955061; CCW59816.1; -; Genomic_DNA.
DR   EnsemblProtists; CCW59816; CCW59816; GSEM1_T00000363001.
DR   OrthoDB; 962356at2759; -.
DR   Proteomes; UP000027080; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.2150; -; 1.
DR   InterPro; IPR007823; RRP8.
DR   InterPro; IPR042036; RRP8_N.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   PANTHER; PTHR12787; PTHR12787; 1.
DR   Pfam; PF05148; Methyltransf_8; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|RuleBase:RU365074};
KW   Nucleus {ECO:0000256|RuleBase:RU365074};
KW   rRNA processing {ECO:0000256|RuleBase:RU365074};
KW   S-adenosyl-L-methionine {ECO:0000256|RuleBase:RU365074};
KW   Transferase {ECO:0000256|RuleBase:RU365074}.
FT   REGION          1..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..94
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CCW59816.1"
SQ   SEQUENCE   345 AA;  37865 MW;  6EF06FF77DD626C3 CRC64;
     MAKKTRKKEA RQAARAEQAP SRGNPRPPST PSAGGKSRPT NRSALKGPVV VYGEGATPGR
     RDSANPRDPP PSSKRIFPAA SSASGRQNAS SAAQRRRVLR HHTDDDLLSH FRSQLHASTF
     RLLNEQLYNA PIAFARRLLA DRATFEDYHV GYRQQLARWP VNPNEVIVAA LLGDRRGRFL
     AHKAKGMPGS LPASWVVADM GCGEAAIAAA LGPRGYTVHS FDLVALNERV TVADLAAVPL
     EGNSVDVCIF SLSLMSTDYE KGLFEAFRIL KPNRLLKVVE VRSRIPSAKK FAEMVESIGF
     TLDYQDVVGD YFVAFDFLKN NQEDANPNLA HPPGEVLLPS LYKKR
//
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