ID   W6KSF4_9TRYP            Unreviewed;       855 AA.
AC   W6KSF4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=EF-hand domain-containing family member C2 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GSEM1_T00002703001 {ECO:0000313|EMBL:CCW60251.1};
OS   Phytomonas sp. EM1.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Phytomonas.
OX   NCBI_TaxID=479712 {ECO:0000313|EMBL:CCW60251.1, ECO:0000313|Proteomes:UP000027080};
RN   [1] {ECO:0000313|EMBL:CCW60251.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EM1 {ECO:0000313|EMBL:CCW60251.1};
RA   Genoscope - CEA;
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCW60251.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EM1 {ECO:0000313|EMBL:CCW60251.1};
RX   PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA   Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA   Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA   Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA   Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA   Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA   Wincker P., Dollet M.;
RT   "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT   Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL   PLoS Genet. 10:e1004007-e1004007(2014).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000256|ARBA:ARBA00004430}.
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DR   EMBL; HF955062; CCW60251.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6KSF4; -.
DR   EnsemblProtists; CCW60251; CCW60251; GSEM1_T00002703001.
DR   OrthoDB; 167477at2759; -.
DR   Proteomes; UP000027080; Unassembled WGS sequence.
DR   GO; GO:0005930; C:axoneme; IEA:UniProt.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   Gene3D; 2.30.29.170; -; 3.
DR   InterPro; IPR006602; DM10_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR040193; EFHC1/EFHC2/EFHB.
DR   PANTHER; PTHR12086; EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12086:SF17; EF-HAND DOMAIN-CONTAINING FAMILY MEMBER C2; 1.
DR   Pfam; PF06565; DM10_dom; 3.
DR   SMART; SM00676; DM10; 3.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   PROSITE; PS51336; DM10; 3.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027080}.
FT   DOMAIN          106..218
FT                   /note="DM10"
FT                   /evidence="ECO:0000259|PROSITE:PS51336"
FT   DOMAIN          277..404
FT                   /note="DM10"
FT                   /evidence="ECO:0000259|PROSITE:PS51336"
FT   DOMAIN          459..583
FT                   /note="DM10"
FT                   /evidence="ECO:0000259|PROSITE:PS51336"
FT   DOMAIN          605..640
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
SQ   SEQUENCE   855 AA;  98380 MW;  3AE225C323DF24A3 CRC64;
     MEASSSNVPK EFLRMRDPKL LPPRVGHNWN DQAFRKKNDK PQQLEAEFRG KRAMITANGN
     FQSTTLPEDF NQTAHQLLLS LLTKNRGSLK NPSSSTKLSK RYLTLDDKVL CFYAFFREQA
     PEGGVNDFWH RKVVIDFFLE DDSILIQEPR IPNSGLDGGT FLKRQKVKAD YRQMEQFPGS
     EYLNINYFNV GQSVRINTID FFIYDCDTFT REFLTELGVE VGEPVDCPEN EFTEAYNRHQ
     QQMKAAINGE KLYNMTSSQR KTQAAEAERT TRFLRDSAKI LCFHALLEEN QPETGLGVRN
     VRKLDVLYYI EDDTIAITEQ QTSPEVTSGL YLSRCFLPKC GSLEKANELT FAHRINGVRM
     PYIGPDAYYT HKDLNIGVTI NVLGRPVFLY DCDSYTRFFY AERLGVHLPP AVDVTERFSR
     QAALMKKAGW KPSRGALPDT VRVAVPSAVS PREVAKSPKA DVLRFVLLLE APKTHEDRFR
     RFKLTYYTDT NEVVMHETRV NNLGFNGGCF LKRQQLRKPV PPRGPRNDPN EKERRLKEAQ
     GIAIDTFYNE SDLRIGNVIT VNGLLMRITA MDAHTEAYFM GTAPPPHTPE YVSHLLEALR
     DFLYSRYGNA CKAFLAFDHN RDGVISLSEF TESLKTFQIT DDASLAKEVY FFLRNRQATS
     DPSQPLTTQD VMKWLGEKVS YTRDARRSLP EELLLGNASQ ATEEEEARRL REFQQQRSLI
     ELQARLEGRC FNSVEMFRLA STMPRAYREC RADILTLTNP NRDAIITPVQ LRRCIEEILG
     WSTITQEEMS AIIGFFFPEM PESLYFRQRD ETLDYSVDLP TFQKLFHDIC QLTLLSSDDV
     KTETSVFRYS LKETN
//