ID   W6L8D4_9TRYP            Unreviewed;       363 AA.
AC   W6L8D4;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GSHART1_T00006619001 {ECO:0000313|EMBL:CCW69392.1};
OS   Phytomonas sp. Hart1.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Phytomonas.
OX   NCBI_TaxID=223615 {ECO:0000313|EMBL:CCW69392.1, ECO:0000313|Proteomes:UP000053358};
RN   [1] {ECO:0000313|EMBL:CCW69392.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Hart1 {ECO:0000313|EMBL:CCW69392.1};
RA   Genoscope - CEA;
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCW69392.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hart1 {ECO:0000313|EMBL:CCW69392.1};
RX   PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA   Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA   Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA   Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA   Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA   Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA   Wincker P., Dollet M.;
RT   "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT   Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL   PLoS Genet. 10:e1004007-e1004007(2014).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the RNA 3'-terminal cyclase family. Type 2
CC       subfamily. {ECO:0000256|ARBA:ARBA00007089}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HF955204; CCW69392.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6L8D4; -.
DR   EnsemblProtists; CCW69392; CCW69392; GSHART1_T00006619001.
DR   OrthoDB; 231692at2759; -.
DR   Proteomes; UP000053358; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.65.10.20; RNA 3'-terminal phosphate cyclase domain; 1.
DR   Gene3D; 3.30.360.20; RNA 3'-terminal phosphate cyclase, insert domain; 1.
DR   InterPro; IPR013791; RNA3'-term_phos_cycl_insert.
DR   InterPro; IPR023797; RNA3'_phos_cyclase_dom.
DR   InterPro; IPR037136; RNA3'_phos_cyclase_dom_sf.
DR   InterPro; IPR000228; RNA3'_term_phos_cyc.
DR   InterPro; IPR016443; RNA3'_term_phos_cyc_type_2.
DR   InterPro; IPR020719; RNA3'_term_phos_cycl-like_CS.
DR   InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR   InterPro; IPR036553; RPTC_insert.
DR   NCBIfam; TIGR03400; 18S_RNA_Rcl1p; 1.
DR   PANTHER; PTHR11096; RNA 3' TERMINAL PHOSPHATE CYCLASE; 1.
DR   PANTHER; PTHR11096:SF1; RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN; 1.
DR   Pfam; PF01137; RTC; 1.
DR   Pfam; PF05189; RTC_insert; 1.
DR   SUPFAM; SSF55205; EPT/RTPC-like; 1.
DR   PROSITE; PS01287; RTC; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053358};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT   DOMAIN          4..329
FT                   /note="RNA 3'-terminal phosphate cyclase"
FT                   /evidence="ECO:0000259|Pfam:PF01137"
FT   DOMAIN          175..276
FT                   /note="RNA 3'-terminal phosphate cyclase insert"
FT                   /evidence="ECO:0000259|Pfam:PF05189"
SQ   SEQUENCE   363 AA;  39246 MW;  59162F04E0C6B64B CRC64;
     MHSSEGASLL RHNIVCSILS KKPLHITNIN SDKDPIGIQM YEANFLKFID RVTSGSSFQT
     QDHNTSLVFT PGMILGGVFS HEVPSPRCVT YLLEVAVLLL PFAKFDSRIT FVGATQGALD
     LSVDTFRTVT TRWLQLFGLQ CGIRTISRGA TPGGGGAVIL EVKALRKISY AVSESRGRVR
     RIRGIAFGCR TAPDLPQRSA TTAKGFLLNL IPDVYIVTDV DAGGSRRNES SSGYGVMLVA
     ETTADRCLLS QETVAHAGEA PEEVGRRAAE LLCDQIYEGG CVDGHHQMMV LLLMAVASSD
     APSSMRFGKL TPGAVSIMVL IQSYFGVTFG QREEESFAGS KFPPTNLITC FGSDLVNVWK
     RSS
//