ID   W6LE19_9TRYP            Unreviewed;      1065 AA.
AC   W6LE19;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=Kinesin motor domain-containing protein {ECO:0000259|PROSITE:PS50067};
GN   ORFNames=GSHART1_T00002087001 {ECO:0000313|EMBL:CCW71557.1};
OS   Phytomonas sp. Hart1.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Phytomonas.
OX   NCBI_TaxID=223615 {ECO:0000313|EMBL:CCW71557.1, ECO:0000313|Proteomes:UP000053358};
RN   [1] {ECO:0000313|EMBL:CCW71557.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Hart1 {ECO:0000313|EMBL:CCW71557.1};
RA   Genoscope - CEA;
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCW71557.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hart1 {ECO:0000313|EMBL:CCW71557.1};
RX   PubMed=24516393; DOI=10.1371/journal.pgen.1004007;
RA   Porcel B.M., Denoeud F., Opperdoes F., Noel B., Madoui M.A.,
RA   Hammarton T.C., Field M.C., Da Silva C., Couloux A., Poulain J.,
RA   Katinka M., Jabbari K., Aury J.M., Campbell D.A., Cintron R., Dickens N.J.,
RA   Docampo R., Sturm N.R., Koumandou V.L., Fabre S., Flegontov P., Lukes J.,
RA   Michaeli S., Mottram J.C., Szoor B., Zilberstein D., Bringaud F.,
RA   Wincker P., Dollet M.;
RT   "The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic
RT   Kinetoplastids Reveals a Parasite Tailored for Plants.";
RL   PLoS Genet. 10:e1004007-e1004007(2014).
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HF955211; CCW71557.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6LE19; -.
DR   EnsemblProtists; CCW71557; CCW71557; GSHART1_T00002087001.
DR   OrthoDB; 148196at2759; -.
DR   Proteomes; UP000053358; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   CDD; cd00106; KISc; 1.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR019821; Kinesin_motor_CS.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24115; KINESIN-RELATED; 1.
DR   PANTHER; PTHR24115:SF422; PUTATIVE-RELATED; 1.
DR   Pfam; PF00225; Kinesin; 2.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053358}.
FT   DOMAIN          49..541
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS50067"
FT   REGION          241..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          772..854
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          911..945
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1034..1061
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   BINDING         224..231
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ   SEQUENCE   1065 AA;  121641 MW;  CA88C2A16486A325 CRC64;
     MQRTDSLTLS LQDSPTGADF TNAHTSINSS PSFHRGSDYS LSLQTQGNAM KVYVRVRPYS
     EREIAQQDMS HHSTVRIDSN DPCMITVLDP SRDFRTAATY SFTRCFWSVF ERGDVTNDRD
     LCDTVDAYLN CSPGIPRRLN RSGSLLGRES LASSPSSRSG ELQERSFNDL NALVYGSSGS
     NSVVVDVSIG HPPYASQTEV YHHVGRPILE NALDGYNGCV FVYGQTGSGK TFTMLGYASH
     PNVPAKSRDP TGKPADLSNR SERDPTGPSF GPVSLLSPLP VNFNKPPLKA PEGRALRSKP
     GVDPRELRGI IPRACDELFE ILRRTREKDP SCSYRVEVSY FEIYQDKFYD LIRPQRSLEL
     KVRHNPTSGP YVDGLCYKLV LHEEEAAGVV WKGIHERHTA MTKFNDHSSR GHAILSFNIV
     QLFLDGSGTP RKTQGKLNLV DLAGSERAGQ AGVDRPEYEE GVKINQSLTV LGRVIDCLAD
     LSQNKALSVP VPYRDSKLTL VLMDSIGGNS QTSMVATISP HMINYEEMKQ TLRYASRARQ
     IVNRAVRNED PQVVLIRELR SEVERMQRML GEAGACGYTR EYVLDLEQQV AKLTKKNSSQ
     ALMLATLRAE LERKDFVDPT SAESGAALVP SGPATLTMEQ TGEVVLQEFN NTQKEFATRK
     ANNKREAKAS DANLTTYRRQ NTERARKTLR LQTAEAMYAN TTLTLFKHTM GNLNIVLNYT
     KKKEAIILNS CRNMLLRAYS EVHGTKNQLK SAHEHQMTIC KENFKMMLDT QAQQHQKKLR
     ETVEEGAQQQ QQLMDKHKKA ITQMEEHIQR NRAIYEDSRK GMENEREEVH RQSNAQLTKE
     REQHQQEIKH LRASFGDAMR NSQPPTRELQ QAREVGKLRE EIECRKRTKE VDAERVKHQL
     ENQQLRHQSE LIQKDRQRHK LELEMTDLRR QFTSLEVEKA KKQLEYEEHL AVVLKRQDDI
     INSSNAVLKD WEDKSASMGE DLCRLQKLVN DQDYMNLRQR MRDSVFRQRM NYDKALQDVE
     EKQRRDKQKL FEIMGKAKKV QEEHNESLQR YQEEIQQLLQ KSIDE
//