ID W6MPI2_9ASCO Unreviewed; 635 AA.
AC W6MPI2;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=CBS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=KUCA_T00004598001 {ECO:0000313|EMBL:CDK28614.1};
OS Kuraishia capsulata CBS 1993.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Kuraishia.
OX NCBI_TaxID=1382522 {ECO:0000313|EMBL:CDK28614.1};
RN [1] {ECO:0000313|EMBL:CDK28614.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK28614.1};
RA Genoscope - CEA;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDK28614.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 1993 {ECO:0000313|EMBL:CDK28614.1};
RA Morales L., Noel B., Porcel B., Marcet-Houben M., Hullo M-F., Sacerdot C.,
RA Tekaia F., Leh-Louis V., Despons L., Khanna V., Aury J-M., Barbe V.,
RA Couloux A., Labadie K., Pelletier E., Souciet J-L., Boekhout T.,
RA Gabaldon T., Wincker P., Dujon B.;
RT "Complete DNA sequence of /Kuraishia capsulata/ illustrates novel genomic
RT features among budding yeasts (/Saccharomycotina/).";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HG793129; CDK28614.1; -; Genomic_DNA.
DR AlphaFoldDB; W6MPI2; -.
DR STRING; 1382522.W6MPI2; -.
DR HOGENOM; CLU_009026_1_0_1; -.
DR OrthoDB; 1328303at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd17781; CBS_pair_MUG70_1; 1.
DR CDD; cd17782; CBS_pair_MUG70_2; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR48108:SF34; CBS AND PB1 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G06780); 1.
DR PANTHER; PTHR48108; CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 613..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 84..143
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 151..207
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 258..317
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 326..383
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 487..578
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 70113 MW; 32AA43F3062FC934 CRC64;
MTVPESMMRT PKRAQSALSN ASNGAGADFT DSRKRQSKKD EAIRRKIEND LRKRKNTNMT
DLQGSPRNLR RRPGNYTPGT VMFLKPSEPI VCRPSYTVFE AAQLMSLKKE NCILVVDEDE
ELLGIFTAKD LAFRIVGSNL NANTTMIEEI MTPNPMCCKT STLASDALNL MVGRGFRHLP
VINDSNQIVG VLDITKCYNE AMIKLERMYE SSKKLYDAME GVNAEMGGVS SQPAHVIKYF
DNLKSLIDGP TLNSVLDDST LPIYIDIRAS VFDAANAMKD NHTTAVLVKD SQKFDEVTGI
FTSKDVVLRV IAAGLDPRTC SVIRVMTPKP DYASGGLSVH QALRKMFDGH YLNLPVIDED
SSEIVGIVEV LKLTYATLNQ LKSVQSFGGD SVSGSEIGSA AGANEREGPA WNKFWTSLDN
ETESLHSLDS DSQVNVQVQD VSRSEMAQFA INNDIGPSDS ISVTGMEEKS PAKLRDPQAA
KINFDEAYFF KFKSPVGRIH RISFKPSEGV VSLRDLVSSK FNKQEQLALQ RSQHESFTEN
FDFAISYIDD EGDVVAITTD QDLLDCVLIS KQLQREKADL YIHHPETTPD VDTLPSRRVA
KSSVESKGLP NEVLLSGAIF ALAAAVVVVF TFSRK
//
