ID   W6N2Q0_CLOTY            Unreviewed;       368 AA.
AC   W6N2Q0;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Myo-inositol 2-dehydrogenase {ECO:0000313|EMBL:CDL90673.1};
DE            EC=1.1.1.18 {ECO:0000313|EMBL:CDL90673.1};
GN   ORFNames=CTDIVETGP_0743 {ECO:0000313|EMBL:CDL90673.1};
OS   Clostridium tyrobutyricum DIVETGP.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1408889 {ECO:0000313|EMBL:CDL90673.1, ECO:0000313|Proteomes:UP000019482};
RN   [1] {ECO:0000313|EMBL:CDL90673.1, ECO:0000313|Proteomes:UP000019482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DIVETGP {ECO:0000313|EMBL:CDL90673.1,
RC   ECO:0000313|Proteomes:UP000019482};
RA   Soggiu A., Piras C., Gaiarsa S., Sassera D., Roncada P., Bendixen E.,
RA   Brasca M., Bonizzi L.;
RT   "Draft Genome Sequence of Clostridium tyrobutyricum Strain DIVETGP,
RT   Isolated from Cow's Milk for Grana Padano Production.";
RL   Genome Announc. 3:213-215(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDL90673.1}.
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DR   EMBL; CBXI010000008; CDL90673.1; -; Genomic_DNA.
DR   RefSeq; WP_017895348.1; NZ_CBXI010000008.1.
DR   AlphaFoldDB; W6N2Q0; -.
DR   GeneID; 29419730; -.
DR   OrthoDB; 9815825at2; -.
DR   Proteomes; UP000019482; Unassembled WGS sequence.
DR   GO; GO:0050112; F:inositol 2-dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR008354; Glc-Fru_OxRdtase_bac.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43249:SF1; D-GLUCOSIDE 3-DEHYDROGENASE; 1.
DR   PANTHER; PTHR43249; UDP-N-ACETYL-2-AMINO-2-DEOXY-D-GLUCURONATE OXIDASE; 1.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR   PRINTS; PR01775; GLFROXRDTASE.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:CDL90673.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019482}.
FT   DOMAIN          4..129
FT                   /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01408"
FT   DOMAIN          143..349
FT                   /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02894"
SQ   SEQUENCE   368 AA;  41705 MW;  09431B0A70671479 CRC64;
     MNKLKFAIIG CGRISYKHVE ALINNKVGAE LVCTCDIVLD KAKEKGKEYS DKLNENIQVK
     VYSDYKKMLE NEDIDVVTIA TESGYHPEIA MYCMNKKKNV IVEKPMALSI DDANNMIKCA
     KDNNVKLCIS HQNRFNVPIQ KLRKAIDENR FGRLINGTAR ILWNRNMNYY KQAPWRGTWK
     LDGGTLMNQC IHDIDLLQWM LGGEIDTVYS QSDTFMRDIE AEDFGAVIIR FKNGAIGMIE
     GSACVYPKNL EETLSIFGQN GAVCIGGLAV NKIETWRFND NKDNEEDILK AQEGDPDTVY
     GFGHTPLFKD MIDAINDNRE PLVNGEEGKK GMSIILAAYK SRLTGQPVKF PFDNFSTMDM
     INIDKIHK
//