ID   W6N7H8_CLOTY            Unreviewed;       389 AA.
AC   W6N7H8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Vancomycin B-type resistance protein VanW {ECO:0000313|EMBL:CDL91299.1};
GN   ORFNames=CTDIVETGP_1369 {ECO:0000313|EMBL:CDL91299.1};
OS   Clostridium tyrobutyricum DIVETGP.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1408889 {ECO:0000313|EMBL:CDL91299.1, ECO:0000313|Proteomes:UP000019482};
RN   [1] {ECO:0000313|EMBL:CDL91299.1, ECO:0000313|Proteomes:UP000019482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DIVETGP {ECO:0000313|EMBL:CDL91299.1,
RC   ECO:0000313|Proteomes:UP000019482};
RA   Soggiu A., Piras C., Gaiarsa S., Sassera D., Roncada P., Bendixen E.,
RA   Brasca M., Bonizzi L.;
RT   "Draft Genome Sequence of Clostridium tyrobutyricum Strain DIVETGP,
RT   Isolated from Cow's Milk for Grana Padano Production.";
RL   Genome Announc. 3:213-215(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDL91299.1}.
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DR   EMBL; CBXI010000023; CDL91299.1; -; Genomic_DNA.
DR   RefSeq; WP_017894653.1; NZ_CBXI010000023.1.
DR   AlphaFoldDB; W6N7H8; -.
DR   GeneID; 29420922; -.
DR   OrthoDB; 9797191at2; -.
DR   Proteomes; UP000019482; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007391; Vancomycin_resist_VanW.
DR   InterPro; IPR022029; YoaR-like_PG-bd.
DR   PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR   Pfam; PF12229; PG_binding_4; 1.
DR   Pfam; PF04294; VanW; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019482};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          100..210
FT                   /note="YoaR-like putative peptidoglycan binding"
FT                   /evidence="ECO:0000259|Pfam:PF12229"
SQ   SEQUENCE   389 AA;  42839 MW;  8ADC6A1CD97B9B3F CRC64;
     MDEMNNPRRS RKSRNKARTN RLMIIIIACV IAFLGVAAGF MVYHYNEVKY WDKLIYPGVT
     VESLDLSGKT KAEAKNMINK AYVEKLKNKK IIISASDSTY TLNYSNINGK FNVDDIVNQA
     YSYGKNSNIL KKYSMIKSSN KVIYKLKFTY DEKPVKELVK KIAGDVDRDP ENAAISMGGI
     GFNITPEVNG LKLDQKDLEK QLLSKIDGDV TGDLKINAKI DTVAASIKSS DLQKVNTLIS
     NFSTNYGSVS SSQRANNIEL ATKSINGTVI MPGEEFSFNG VVGERTAAKG YKAAPVIIGD
     KLEDGLGGGI CQVSTTLYNA VNAAGLTSTE RVHHTMPVHY VAKGMDATVD YGNIDYKFRN
     DFKYPVYVQG YTSGGSVVFN IYSNSAEKK
//