ID W6NEE8_CLOTY Unreviewed; 517 AA.
AC W6NEE8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit {ECO:0000313|EMBL:CDL90402.1};
DE EC=2.8.3.8 {ECO:0000313|EMBL:CDL90402.1};
GN ORFNames=CTDIVETGP_0472 {ECO:0000313|EMBL:CDL90402.1};
OS Clostridium tyrobutyricum DIVETGP.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1408889 {ECO:0000313|EMBL:CDL90402.1, ECO:0000313|Proteomes:UP000019482};
RN [1] {ECO:0000313|EMBL:CDL90402.1, ECO:0000313|Proteomes:UP000019482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DIVETGP {ECO:0000313|EMBL:CDL90402.1,
RC ECO:0000313|Proteomes:UP000019482};
RA Soggiu A., Piras C., Gaiarsa S., Sassera D., Roncada P., Bendixen E.,
RA Brasca M., Bonizzi L.;
RT "Draft Genome Sequence of Clostridium tyrobutyricum Strain DIVETGP,
RT Isolated from Cow's Milk for Grana Padano Production.";
RL Genome Announc. 3:213-215(2015).
CC -!- SIMILARITY: Belongs to the 3-oxoacid CoA-transferase family.
CC {ECO:0000256|ARBA:ARBA00007154, ECO:0000256|PIRNR:PIRNR000858}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL90402.1}.
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DR EMBL; CBXI010000006; CDL90402.1; -; Genomic_DNA.
DR RefSeq; WP_017751104.1; NZ_CBXI010000006.1.
DR AlphaFoldDB; W6NEE8; -.
DR SMR; W6NEE8; -.
DR GeneID; 29419800; -.
DR OrthoDB; 9805230at2; -.
DR Proteomes; UP000019482; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046952; P:ketone body catabolic process; IEA:InterPro.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 2.
DR InterPro; IPR014388; 3-oxoacid_CoA-transferase.
DR InterPro; IPR004165; CoA_trans_fam_I.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR43293; ACETATE COA-TRANSFERASE YDIF; 1.
DR PANTHER; PTHR43293:SF1; ACETATE COA-TRANSFERASE YDIF; 1.
DR Pfam; PF01144; CoA_trans; 1.
DR PIRSF; PIRSF000858; SCOT-t; 1.
DR SMART; SM00882; CoA_trans; 2.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019482};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000858}.
FT ACT_SITE 324
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000858-1"
SQ SEQUENCE 517 AA; 56010 MW; 5DCF698C62914CB9 CRC64;
MGVKFLKACD AVEMVKDGDL IATSGFVGSL CSEELSIALE KRFEETGHPK NLTLVYSAAQ
GDGKGKGADH FAHEGMLKRV AGGHWNLSPK LGKMAVENKI EAYNLPQGTI AQLFRDIAGK
RIGTITHVGL NTFVDPRIQG GKLNDITKED VVKLINIEGQ EKLLYKAFPI DVCFLRGSFA
DENGNISLER EVGTIDVLSI AQACRNSGGI VIVQVEKVVS SGTLDPRLVK IPGIYVDVVV
VAKPEHHEQF FGCNGYDPAL TGEVRVPLKA IQYPELNARK IIARRAAMEL KPDAVVNLGI
GIPEVISMVA NEEEIGEYMT MTVEAGAVGG VPLGGTGFGA CINPESILDE AYQFDFYDGG
GTDIAFLGLA QVDRHGNINV SKFGPRIAGC GGFINITQNA KRVLFCGTFT AGGLKIDTGN
GKLKIIQEGR SIKFLNEVEQ ITFSGEYAIK TKQPVTYITE RAVFELKEEG LYITEIAPGI
DLEKDVLGLM EFKPKIDKSL KLMDEKIFHN GLMGLKK
//
