ID   W6NGD8_CLOTY            Unreviewed;       382 AA.
AC   W6NGD8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:CDL91107.1};
DE            EC=1.1.1.1 {ECO:0000313|EMBL:CDL91107.1};
GN   ORFNames=CTDIVETGP_1177 {ECO:0000313|EMBL:CDL91107.1};
OS   Clostridium tyrobutyricum DIVETGP.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1408889 {ECO:0000313|EMBL:CDL91107.1, ECO:0000313|Proteomes:UP000019482};
RN   [1] {ECO:0000313|EMBL:CDL91107.1, ECO:0000313|Proteomes:UP000019482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DIVETGP {ECO:0000313|EMBL:CDL91107.1,
RC   ECO:0000313|Proteomes:UP000019482};
RA   Soggiu A., Piras C., Gaiarsa S., Sassera D., Roncada P., Bendixen E.,
RA   Brasca M., Bonizzi L.;
RT   "Draft Genome Sequence of Clostridium tyrobutyricum Strain DIVETGP,
RT   Isolated from Cow's Milk for Grana Padano Production.";
RL   Genome Announc. 3:213-215(2015).
CC   -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00007358}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDL91107.1}.
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DR   EMBL; CBXI010000019; CDL91107.1; -; Genomic_DNA.
DR   RefSeq; WP_017751027.1; NZ_CBXI010000019.1.
DR   AlphaFoldDB; W6NGD8; -.
DR   GeneID; 29418808; -.
DR   OrthoDB; 9804734at2; -.
DR   Proteomes; UP000019482; Unassembled WGS sequence.
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd08551; Fe-ADH; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR   PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR   PROSITE; PS00913; ADH_IRON_1; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:CDL91107.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019482}.
FT   DOMAIN          9..373
FT                   /note="Alcohol dehydrogenase iron-type/glycerol
FT                   dehydrogenase GldA"
FT                   /evidence="ECO:0000259|Pfam:PF00465"
SQ   SEQUENCE   382 AA;  41278 MW;  32C5D902E0A960EB CRC64;
     MNYSIFQSPR DILYGQDTVN LVGEKAIKFG KKVMIITGKH SSKKTGALDK VLDSLKKNNL
     DFVVFNDIES DPSANTVRKG VEVAGENGID IIVALGGGSA LDASKAISMV ASNGGDIVDY
     EDNIPHKEGI PIIAVPTTAG TGSEVSKFSI ITDTDRKIKM LIANDLLIPK VAILDPKLTL
     MMPPSVTAAT GMDAFTHAIE AYISKASQRT SDLYAIKAIE LISRNLAKAV LKGDDLEARE
     NMMVGQMYAG LAFTNSSTAL VHSMSRPLGA YYGVPHGLAN ALLLPEVMKF NRAACADRFK
     AIAAAMGENI HGKSTREISY MTIDTIKNVF LETGLPTKLK EVGVDESNFE NMAEDAIKSR
     TTLLNPRKPT VEQLIEIYKT IY
//