ID W6NUU0_HAECO Unreviewed; 245 AA.
AC W6NUU0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=BLOC-1-related complex subunit 5 {ECO:0000256|ARBA:ARBA00022300};
GN ORFNames=HCOI_01043800 {ECO:0000313|EMBL:CDL94575.1}, HCOI_01596600
GN {ECO:0000313|EMBL:CDL95772.1};
OS Haemonchus contortus (Barber pole worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Trichostrongylidae; Haemonchus.
OX NCBI_TaxID=6289 {ECO:0000313|EMBL:CDL95772.1};
RN [1] {ECO:0000313|EMBL:CDL95772.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISE/inbred ISE {ECO:0000313|EMBL:CDL95772.1};
RA Aslett M.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDL95772.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ISE/inbred ISE {ECO:0000313|EMBL:CDL95772.1};
RA Laing R., Kikuchi T., Martinelli A., Tsai I.J., Beech R.N., Redman E.,
RA Holroyd N., Bartley D.J., Beasley H., Britton C., Curran D., Devaney E.,
RA Gilabert A., Jackson F., Hunt M., Johnston S., Kryukov I., Li K.,
RA Morrison A.A., Reid A.J., Sargison N., Saunders G., Wasmuth J.D.,
RA Wolstenholme A., Berriman M., Gilleard J.S., Cotton J.A.;
RT "The genome and transcriptome of Haemonchus contortus: a key model parasite
RT for drug and vaccine discovery.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004122}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004122}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004122}.
CC -!- SIMILARITY: Belongs to the BORCS5 family.
CC {ECO:0000256|ARBA:ARBA00010235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDL95772.1}.
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DR EMBL; CAVP010058391; CDL94575.1; -; Genomic_DNA.
DR EMBL; CAVP010059384; CDL95772.1; -; Genomic_DNA.
DR AlphaFoldDB; W6NUU0; -.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032418; P:lysosome localization; IEA:InterPro.
DR CDD; cd22789; BORCS5-like; 1.
DR InterPro; IPR018780; TBORCS5.
DR PANTHER; PTHR31634; BLOC-1-RELATED COMPLEX SUBUNIT 5; 1.
DR PANTHER; PTHR31634:SF2; BLOC-1-RELATED COMPLEX SUBUNIT 5; 1.
DR Pfam; PF10158; LOH1CR12; 1.
PE 3: Inferred from homology;
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 27189 MW; 0825424FE909CD35 CRC64;
MGNEQSSSGT SPQASTNSTF SFLSGKGNSK KSKGIVVVSG GNAKVETLDD DEVYKRFKEI
PRFLPILRHA IGKKDIPQSE IPHKVNSRPL FRMATRFQQH LKICATTIAA DQSHINQLVK
SVDASVVAIS NRLNERKKVT DNLIANLQDL DKLRDDVVHI RLLFEHLVPM VETINEILVP
SERLPPLALS RVLDRTPVST SESSEQSTPR HNPSGSGSQP RSALSQDKTT RISPIEEVRV
VDRRK
//
