ID   W6PWA8_PENRF            Unreviewed;       374 AA.
AC   W6PWA8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=mitogen-activated protein kinase {ECO:0000256|ARBA:ARBA00012411};
DE            EC=2.7.11.24 {ECO:0000256|ARBA:ARBA00012411};
GN   ORFNames=PROQFM164_S01g002339 {ECO:0000313|EMBL:CDM28528.1};
OS   Penicillium roqueforti (strain FM164).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM28528.1};
RN   [1] {ECO:0000313|EMBL:CDM28528.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FM164 {ECO:0000313|EMBL:CDM28528.1};
RX   PubMed=24407037; DOI=10.1038/ncomms3876;
RA   Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA   Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA   Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT   "Multiple recent horizontal transfers of a large genomic region in cheese
RT   making fungi.";
RL   Nat. Commun. 5:2876-2876(2014).
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR   EMBL; HG792015; CDM28528.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6PWA8; -.
DR   STRING; 1365484.W6PWA8; -.
DR   OMA; VVNDKCV; -.
DR   OrthoDB; 2256760at2759; -.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004707; F:MAP kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR003527; MAP_kinase_CS.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR24055; MITOGEN-ACTIVATED PROTEIN KINASE; 1.
DR   PANTHER; PTHR24055:SF158; MITOGEN-ACTIVATED PROTEIN KINASE P38A-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS01351; MAPK; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:CDM28528.1};
KW   Transferase {ECO:0000313|EMBL:CDM28528.1}.
FT   DOMAIN          20..301
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   374 AA;  43205 MW;  D9F69925BC37D5AD CRC64;
     MATFITHKIM GTTLQTTERY TDLKARGVGA FGVICSAHDS MANRTMAIKK IGKPFESSSR
     VKRTYREVHL MNNLKHDNLI NMTDIFISPA EDLYIVMDCC MTDLHHLIQS RSKPLEDRFT
     QFFTYQLLRG LKFIHSAGVI HRDVKPSNIL ITENCDLKIC DFGLAREQDH QMTGYVSTRY
     YRAPEIMLTW QRYTYGVDIW STGCILAEML LGKVFLPARD NVHHFKLITE IFGKPPREIM
     ETVYSDITMD FVNSLPETKP RSLGATLGDV DPEAVHLLEK MLDIDPQKRI TADDALTDPY
     VSSYSDSNDE PECEKQIDLS LLDSEMTTDE WKSKMYFEIL NYHTGSYNWE DTDPKAHEGR
     FEDWLRQEIM VGTY
//