ID W6Q472_PENRF Unreviewed; 428 AA.
AC W6Q472;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=GPCR, rhodopsin-like superfamily {ECO:0000313|EMBL:CDM28954.1};
GN ORFNames=PROQFM164_S01g002765 {ECO:0000313|EMBL:CDM28954.1};
OS Penicillium roqueforti (strain FM164).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM28954.1};
RN [1] {ECO:0000313|EMBL:CDM28954.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FM164 {ECO:0000313|EMBL:CDM28954.1};
RX PubMed=24407037; DOI=10.1038/ncomms3876;
RA Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT "Multiple recent horizontal transfers of a large genomic region in cheese
RT making fungi.";
RL Nat. Commun. 5:2876-2876(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HG792015; CDM28954.1; -; Genomic_DNA.
DR AlphaFoldDB; W6Q472; -.
DR STRING; 1365484.W6Q472; -.
DR OMA; FWLQIGD; -.
DR OrthoDB; 2682754at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR022596; GPR1_C.
DR PANTHER; PTHR23112; G PROTEIN-COUPLED RECEPTOR 157-RELATED; 1.
DR PANTHER; PTHR23112:SF0; G-PROTEIN COUPLED RECEPTOR 157; 1.
DR Pfam; PF05462; Dicty_CAR; 1.
DR Pfam; PF11970; GPR_Gpa2_C; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..306
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 320..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 47872 MW; AF03DEA5A59F472E CRC64;
MSAVILMGLI PGNKHSLAAR LTTSAQLTID PLSESHREGL IAISVLAFLS LIATSILLGF
ITYRLFFWRS SYTRYIGYNQ YIILIYNLVL ADFLQSLGFI ISLQWILTNK IESSSAACFL
QGLWLQIGDP SSGLFVFAIA FHTFLLVVCG RKMSHKFFVS FVVGIWAFVV LMLIIPLAQH
GPGIFVLSGA WCWISDDYEI ARLWTHYVWI FLAEFGTIIL YAVMYFQLRR QISASAILGN
SQLESLKRLR RVVGYMTIYP IIYLVLSLPI AASRMATSHG DTPNIVFFCC SGAIITSSGL
VDVILYTLTR RNLIIDSEPS EDRSYHNYNG SKGKRGGNNL TTVTADPKHT VGGTYIDEID
RNGSTDNIVS PTAHGYHARD QEMMPIGQVY QETTIVITHE PAYPTEESSK RSSKENFPDR
PSQSGWRG
//
