ID   W6Q4E6_PENRF            Unreviewed;      1282 AA.
AC   W6Q4E6;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE            EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
GN   ORFNames=PROQFM164_S02g001365 {ECO:0000313|EMBL:CDM31215.1};
OS   Penicillium roqueforti (strain FM164).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM31215.1};
RN   [1] {ECO:0000313|EMBL:CDM31215.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FM164 {ECO:0000313|EMBL:CDM31215.1};
RX   PubMed=24407037; DOI=10.1038/ncomms3876;
RA   Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA   Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA   Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT   "Multiple recent horizontal transfers of a large genomic region in cheese
RT   making fungi.";
RL   Nat. Commun. 5:2876-2876(2014).
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DR   EMBL; HG792016; CDM31215.1; -; Genomic_DNA.
DR   STRING; 1365484.W6Q4E6; -.
DR   OMA; ILYWAHH; -.
DR   OrthoDB; 335467at2759; -.
DR   GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd09138; PLDc_vPLD1_2_yPLD_like_1; 1.
DR   CDD; cd09141; PLDc_vPLD1_2_yPLD_like_2; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 3.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   InterPro; IPR015679; PLipase_D_fam.
DR   PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR   PANTHER; PTHR18896:SF186; PHOSPHOLIPASE D; 1.
DR   Pfam; PF13091; PLDc_2; 1.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00022963}.
FT   DOMAIN          291..318
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          1047..1074
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   REGION          1..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          423..757
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        423..580
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        592..690
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        705..721
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        738..757
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1282 AA;  143023 MW;  7A68A02171F5074F CRC64;
     MSNQDDLAYG GYYQGSERGS GDGSRGLGDT FKKFRDTYKS HGSSGPGNQG YQGQSQTEPQ
     YGYDQSQSTS GQQQNPNYYG KPQKEDKLSD FLEKLQGTVT ELGSEFAQKI GTTIDPQAYA
     QYGPSNTNTE HRFDSFAPVR EHNDAKWYVD GCGYFWAVSR ALENARESIW ILDWWLSPEL
     YLRRPPAKNE QYRLDRMLQA AAQRGVRVNV IVYKEVTQAL TLSSSHTKHA LEDLHPNISV
     FRHPDHLPDR QEMTADIEST LQNLSLDSKS LSKMSKDTLK GLYGMRDDVI LYWAHHEKLC
     LIDGQIAFMG GLDLCFGRWD TNQHNLSDLH PSDVNQTVFP GQDYNNSRVL DFEDVVHWEN
     NQLDRKTMSR MGWSDISVSL HGAAVEDLRR HFVERWNFIY DLKYKIRNES RYTRLALHGR
     PAYSTGQQQA ASPQPNLYPS GQASPQSQQP APSWQQKPSG VASASTYPPP PGQTSSSSYQ
     EPQSHSQSHS QSQSQPQSNS YPSGQASTQG QSTVPSWQQK PSEVASSSTY PPPPGQTSSA
     SYQEPHSQSQ TQPQSNVYPS GQASTQGQST VPSWQEKPSG VASPTYPPPP GQTSSSSYQE
     SHSQSQPQPQ HQEPAGVYQP HTSASTSGYA PSPTQISSNQ HQYQQQNTSP SYQAENASTY
     HPVPSQTPLG YQPQSAQSQG HDASQYSYTG NSFPPPPPGP PPAQSSADTS YQPYHGQQQE
     QTPYYPPPPG QEASHSNTRG IDDYHQYEGD RDRGFAPRRL REDLTQYGTS LRGQLAGQIH
     QYQDRLVTYG RPSSSQGRGG MSCQIVRSCA KWSNGTQIEH SIADAYCAII RNSEHFVYIE
     NQFFITATGN SQHPVKNQIG AAIVERILRA ARAGQKYKIV VVIPSVPCFA GDLRDDATLG
     TRAIMEFQYN SINRGGHSIM ELIAKEGFNP MEYIRFYNLR NYDRINNGGI MAAAEQQSGV
     KYEDARREYD LNTAGPGGYA PSTTRSAFDT TAPFEKYQQA ARQVQGGHAS SGRWDSVSEC
     YMLNGEDIRK VPWDGHPDAE INAFVSEELY VHSKVMIADD RVVVCGSANL NDRSQLGDHD
     SEIAVIIEDF TPVASTMDGK PWTASRFASS LRRQLFRKHL GLLPPQDYER PDANFEPVGV
     PNNFDFDCPE SKIVADPLAD TAQSLWNSRA HTNTEVFRKV FHAVPDDTIR NWTEYKEFYE
     YYFHKTEVSP EGKEGSARPA RFQWGHVVSD DFAPGAEGAK QVKELLSQVK GTLVEMPLMF
     LIEEDVAKSG LTLNDVTEPL YT
//