ID   W6QQ06_PENRF            Unreviewed;       735 AA.
AC   W6QQ06;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   03-MAY-2023, entry version 27.
DE   RecName: Full=Carboxylesterase type B domain-containing protein {ECO:0000259|Pfam:PF00135};
GN   ORFNames=PROQFM164_S04g001040 {ECO:0000313|EMBL:CDM36159.1};
OS   Penicillium roqueforti (strain FM164).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM36159.1};
RN   [1] {ECO:0000313|EMBL:CDM36159.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FM164 {ECO:0000313|EMBL:CDM36159.1};
RX   PubMed=24407037; DOI=10.1038/ncomms3876;
RA   Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA   Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA   Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT   "Multiple recent horizontal transfers of a large genomic region in cheese
RT   making fungi.";
RL   Nat. Commun. 5:2876-2876(2014).
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DR   EMBL; HG792018; CDM36159.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6QQ06; -.
DR   STRING; 1365484.W6QQ06; -.
DR   ESTHER; penro-w6qq06; Fungal_carboxylesterase_lipase.
DR   OMA; PTMFTTV; -.
DR   OrthoDB; 1433837at2759; -.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR   GO; GO:0072330; P:monocarboxylic acid biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR   PANTHER; PTHR43142:SF6; PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01710)-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..735
FT                   /note="Carboxylesterase type B domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004882248"
FT   DOMAIN          180..650
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   735 AA;  80177 MW;  F60DF64163F151F1 CRC64;
     MESKFAILAF CLLLSHGLAE QRHPHVGSLG DLRVLHYNNL GPQNNGTSAI LAHDRSSYFD
     AVAKCIAIGE KLFPWSSSES NSQVHSELGY ELDYLIFAKE IRDDDYFWLS EEENRKICSA
     FSIAHRKIIQ KPCNVKLPAL CTSSPPGTTD RDRAVRETTK LTVTSHDYTL TGYRDARSFR
     FLGVPFASPP INDLRFAPPQ AYTGSNNIDA TSMGNSCIQS ASALSTVSIG GMSEDCLYLN
     VFTPFLPHNI TKNTALRPVA VYLYGGAFTK GTAAMIDYDG GNFASRSDVV VVTVNYRLGA
     LGFLSTGKLT TGSYGIQDQI MALQWVQKHI SALGGDPSHV TVFGQSSGGQ SVVALLSSSA
     AKGLFSGALV QSANFDLPWF PRALYSKYIA PEVGNAVGCD GNAPEATLLN CLRSVPASMY
     LDNSTDFQTA TKSFSSNKAN HFYHNTELLS ASEPFMPMVD DTGSGVIDDQ FNILLSKNKL
     PINVPTMFTN VRDEASLYMA IFGSTQSPLA TLLSVIFGDT LARKIISSGA YKVNDSDHDA
     VLNAASDAVS HSQWTCPQGY LLENSISIFP VLYQVQIADG HAETSNMPGI CYPNTAYNAS
     CHTSDVLLAW GTLNTKTQDV YPYYDDLDIL HSQLVHDVFG AFFRERNPNP DLEFLKIRGP
     AYASTLSIFG GESVGSNSSF GRSEKRFLIE EYTASTRNMT LLGMPPSTTA NFEDEEICAV
     LRDYGFTFQR ARLSD
//