ID W6QWJ8_PENRF Unreviewed; 717 AA.
AC W6QWJ8;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Kinesin, motor domain {ECO:0000313|EMBL:CDM33897.1};
GN ORFNames=PROQFM164_S03g000621 {ECO:0000313|EMBL:CDM33897.1};
OS Penicillium roqueforti (strain FM164).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1365484 {ECO:0000313|EMBL:CDM33897.1};
RN [1] {ECO:0000313|EMBL:CDM33897.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FM164 {ECO:0000313|EMBL:CDM33897.1};
RX PubMed=24407037; DOI=10.1038/ncomms3876;
RA Cheeseman K., Ropars J., Renault P., Dupont J., Gouzy J., Branca A.,
RA Abraham A.L., Ceppi M., Conseiller E., Debuchy R., Malagnac F., Goarin A.,
RA Silar P., Lacoste S., Sallet E., Bensimon A., Giraud T., Brygoo Y.;
RT "Multiple recent horizontal transfers of a large genomic region in cheese
RT making fungi.";
RL Nat. Commun. 5:2876-2876(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; HG792017; CDM33897.1; -; Genomic_DNA.
DR AlphaFoldDB; W6QWJ8; -.
DR STRING; 1365484.W6QWJ8; -.
DR OMA; NRHPQKA; -.
DR OrthoDB; 47485at2759; -.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24115:SF1014; KINESIN-LIKE PROTEIN SUBITO; 1.
DR PANTHER; PTHR24115; KINESIN-RELATED; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283}.
FT DOMAIN 10..479
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 187..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..717
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 111..118
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 717 AA; 79886 MW; 93480DC0116EE26A CRC64;
MPPKQPQTSL FQVYLRLRPP MTPNPNECDR FLNVEAPEAS QEETEIVSPA STHVTLQPPN
DTRKRAVERF GFTKVFEETA SQLDVFHDTG MEPIIRGVLK ENRDGLVATL GVTGSGKSHT
ILGSKTQRGM TQMALDVIFR SLESTNKTDH GSITPVMLAS LAVADASEAQ LFSAQTFLEA
VYGEPNGRTS RAQTPMSPSR ANTPLTEPTP ALNFPRRHIR ERPCALPRLP DMSHLTVDMD
SNADYVVLVS MYEVYNDRIF DLLSPSIASG QGNMSRGNNQ KDRRRPLLFK STEGSPDRKL
VAGLRKIACS SYEEALAILD VGLTERKVTG TGMNSVSSRS HGFFSLEVKK RTYSKRTGEQ
NWAGNALTVV DLAGSERART AKTAGATLAE AGKINESLMY LGQCLQMQSN IQDGMKTALV
PYRQCKLTEL LFSNSFPSSH QMSRGQYPQK AIMIVTADPV GDFNATSQIL RYSALAREVT
VPRIPSICES ILSAASGSHR SISGSTSPNF DSAEELERAA AEITRLTRDC HGLAVKLAEE
EIARADVEMR LSAAEERCLM IEQDVREECW AEMDEKMEEE RRRWQRAWDE QIGRNDEHID
KKVELVSRGF QIFEDSASNE RVEELEQEND QLRRKLAAFE REMHNQSPTR KNRPKNATSA
RSNPLGRGSD VENALQRMDQ LKLADTMFAP PSPGSSPIKK TRKMGTRKWD LAPEDQI
//
