ID W6T924_9LACO Unreviewed; 430 AA.
AC W6T924;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=DNA-directed DNA polymerase {ECO:0000313|EMBL:ETY74368.1};
GN ORFNames=LFAB_07850 {ECO:0000313|EMBL:ETY74368.1};
OS Lactiplantibacillus fabifermentans T30PCM01.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1400520 {ECO:0000313|EMBL:ETY74368.1, ECO:0000313|Proteomes:UP000019247};
RN [1] {ECO:0000313|EMBL:ETY74368.1, ECO:0000313|Proteomes:UP000019247}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30PCM01 {ECO:0000313|EMBL:ETY74368.1,
RC ECO:0000313|Proteomes:UP000019247};
RX PubMed=24558238;
RA Treu L., Vendramin V., Bovo B., Giacomini A., Corich V., Campanaro S.;
RT "Genome Sequence of Lactobacillus fabifermentans Strain T30PCM01, Isolated
RT from Fermenting Grape Marc.";
RL Genome Announc. 2:e00060-e00014(2014).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETY74368.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWWK01000034; ETY74368.1; -; Genomic_DNA.
DR RefSeq; WP_033613923.1; NZ_KK036487.1.
DR AlphaFoldDB; W6T924; -.
DR STRING; 1400520.LFAB_07850; -.
DR PATRIC; fig|1400520.3.peg.1542; -.
DR eggNOG; COG0389; Bacteria.
DR HOGENOM; CLU_012348_5_0_9; -.
DR OrthoDB; 9808813at2; -.
DR Proteomes; UP000019247; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProt.
DR CDD; cd01700; PolY_Pol_V_umuC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR024728; PolY_HhH_motif.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF35; DNA REPAIR PROTEIN HOMOLOG YOBH; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF11798; IMS_HHH; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932,
KW ECO:0000313|EMBL:ETY74368.1};
KW Mutator protein {ECO:0000256|ARBA:ARBA00022457};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932,
KW ECO:0000313|EMBL:ETY74368.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022932, ECO:0000313|EMBL:ETY74368.1}.
FT DOMAIN 16..205
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 430 AA; 48794 MW; 6E5D29FC43E2BD68 CRC64;
MVTPLDDADR LPVHDIMCID CKSFYASTEA IRRGEYPLAA KIAVLSREES NGGLILAASP
DTKKDYGVKL GTRKFELQPM MDIELVAPHM QTYIQLNYRV NQIFRQFTDD QHWYVYSVDE
AFIDVTHSHK LFGSNEAIAH QIQKKVFDQT GIVTTIGIGP NPLMAKLALD NAAKEQAPWQ
ATWTYDDVPQ KVWQIDDLTD FWSIGQKTAD KLKNLGIHNI YELAHTDRRQ LQQNFGVLGD
ALYFHSWGID YSDLAKRYVP RAENKGYGNS QVLMRNYTTR ADIETVLFEI ADQVATRLRQ
HQVLGEVISI QVGFATPDAR ARRGWSAQTK VDPTNQTNDL IRAVQYLFES RWEGDALRNV
GVRVNRISRP SSLQLSLFSD VKRDAANLRL EHTIDQIRSR YGYQAIVRGY SKTAAGTAIE
RSKLVGGHQA
//
