ID   W6T927_9LACO            Unreviewed;       348 AA.
AC   W6T927;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Molecular chaperone GroES {ECO:0000313|EMBL:ETY74951.1};
GN   ORFNames=LFAB_04365 {ECO:0000313|EMBL:ETY74951.1};
OS   Lactiplantibacillus fabifermentans T30PCM01.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactiplantibacillus.
OX   NCBI_TaxID=1400520 {ECO:0000313|EMBL:ETY74951.1, ECO:0000313|Proteomes:UP000019247};
RN   [1] {ECO:0000313|EMBL:ETY74951.1, ECO:0000313|Proteomes:UP000019247}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T30PCM01 {ECO:0000313|EMBL:ETY74951.1,
RC   ECO:0000313|Proteomes:UP000019247};
RX   PubMed=24558238;
RA   Treu L., Vendramin V., Bovo B., Giacomini A., Corich V., Campanaro S.;
RT   "Genome Sequence of Lactobacillus fabifermentans Strain T30PCM01, Isolated
RT   from Fermenting Grape Marc.";
RL   Genome Announc. 2:e00060-e00014(2014).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETY74951.1}.
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DR   EMBL; AWWK01000022; ETY74951.1; -; Genomic_DNA.
DR   RefSeq; WP_024624745.1; NZ_KK036475.1.
DR   AlphaFoldDB; W6T927; -.
DR   STRING; 1400520.LFAB_04365; -.
DR   PATRIC; fig|1400520.3.peg.857; -.
DR   eggNOG; COG1063; Bacteria.
DR   HOGENOM; CLU_026673_11_3_9; -.
DR   OrthoDB; 9769198at2; -.
DR   Proteomes; UP000019247; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08287; FDH_like_ADH3; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          10..344
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   348 AA;  37163 MW;  97FE7089C8167395 CRC64;
     MKTAVFVEPG KVAARELPKA QVQKPTDAVI KIVRACVCGS DLWWFRGISK RQQPSAVGHE
     AIGIVESVGD EVTNVQPGDF VIVPFTHGCG HCAACLAGFD GDCLNRDEND TEIVGYQGEY
     LRFKNANWAL VKVPGQPSDY TDDQLNDLLT LSDVMATGYH AAAMAEVKAG DTVVVMGDGA
     VGLCGVISAK LLGAKRIIAM SRHADRQALA QEFGATDIIA ERGDEAVKKV FEVTDGAGAD
     AVLECVGTEQ SVDTAVKVGR PGAVVGRVGV PQKAEMNTNN LFWRNIGLRG GIASVTTDDR
     NTLLQAVLAG DIHPGKVFTQ RFDLDHVQQA YEAMDQRKAI KSLLIVSE
//