ID W6TFQ3_9SPIR Unreviewed; 101 AA.
AC W6TFQ3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Variable outer membrane protein {ECO:0000313|EMBL:ETZ17120.1};
GN ORFNames=BDCR2A_01959 {ECO:0000313|EMBL:ETZ17120.1};
OS Borrelia duttonii CR2A.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC Borrelia.
OX NCBI_TaxID=1432657 {ECO:0000313|EMBL:ETZ17120.1, ECO:0000313|Proteomes:UP000019148};
RN [1] {ECO:0000313|EMBL:ETZ17120.1, ECO:0000313|Proteomes:UP000019148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR2A {ECO:0000313|EMBL:ETZ17120.1,
RC ECO:0000313|Proteomes:UP000019148};
RA Schwan T.G., Raffel S.J., Porcella S.F.;
RT "Comparative genomics of relapsing fever spirochetes.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The Vlp and Vsp proteins are antigenically distinct proteins,
CC only one vlp or vsp gene is transcriptionally active at any one time.
CC Switching between these genes is a mechanism of host immune response
CC evasion. {ECO:0000256|ARBA:ARBA00003932}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|ARBA:ARBA00004459}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004459}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the variable small protein (Vsp) family.
CC {ECO:0000256|ARBA:ARBA00008719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETZ17120.1}.
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DR EMBL; AZIT01000100; ETZ17120.1; -; Genomic_DNA.
DR RefSeq; WP_051410812.1; NZ_AZIT01000100.1.
DR AlphaFoldDB; W6TFQ3; -.
DR PATRIC; fig|1432657.3.peg.1821; -.
DR Proteomes; UP000019148; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.120.240; Lipoprotein, type 6; 1.
DR InterPro; IPR001800; Lipoprotein_OspC.
DR InterPro; IPR036437; OspC-like_sf.
DR Pfam; PF01441; Lipoprotein_6; 1.
DR SUPFAM; SSF63515; Outer surface protein C (OspC); 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000019148};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
SQ SEQUENCE 101 AA; 11211 MW; A6E80294FD12A6BC CRC64;
MHVLVKSVDE LAKAIGKKIK QNFEELDVDN GKNNKNGELV AGVFQVMLTV KSKLEELWNT
PEISDELKGK VAGSKNKCKE FVDKIKADSD IAKAEVTDEH L
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