ID   W6TFT1_9SPIR            Unreviewed;       109 AA.
AC   W6TFT1;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Inosine-5'-monophosphate dehydrogenase {ECO:0000313|EMBL:ETZ17108.1};
DE            EC=1.1.1.205 {ECO:0000313|EMBL:ETZ17108.1};
DE   Flags: Fragment;
GN   ORFNames=BDCR2A_01976 {ECO:0000313|EMBL:ETZ17108.1};
OS   Borrelia duttonii CR2A.
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC   Borrelia.
OX   NCBI_TaxID=1432657 {ECO:0000313|EMBL:ETZ17108.1, ECO:0000313|Proteomes:UP000019148};
RN   [1] {ECO:0000313|EMBL:ETZ17108.1, ECO:0000313|Proteomes:UP000019148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR2A {ECO:0000313|EMBL:ETZ17108.1,
RC   ECO:0000313|Proteomes:UP000019148};
RA   Schwan T.G., Raffel S.J., Porcella S.F.;
RT   "Comparative genomics of relapsing fever spirochetes.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC       {ECO:0000256|ARBA:ARBA00005502}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETZ17108.1}.
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DR   EMBL; AZIT01000104; ETZ17108.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6TFT1; -.
DR   Proteomes; UP000019148; Unassembled WGS sequence.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR005990; IMP_DH.
DR   InterPro; IPR001093; IMP_DH_GMPRt.
DR   PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR   Pfam; PF00478; IMPDH; 1.
DR   SMART; SM01240; IMPDH; 1.
DR   SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:ETZ17108.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019148}.
FT   DOMAIN          8..89
FT                   /note="IMP dehydrogenase/GMP reductase"
FT                   /evidence="ECO:0000259|Pfam:PF00478"
FT   NON_TER         109
FT                   /evidence="ECO:0000313|EMBL:ETZ17108.1"
SQ   SEQUENCE   109 AA;  12308 MW;  0ABCCBA10EC86C26 CRC64;
     MDKIVKEALT FDDVSLIPRK SSILPSDVNL KTRLTRNIYL NIPFLSSAMD TVTESRMAIA
     VAKEGGIGVI HKNITIEKQR KEVEIVKSYH RNGIIRNLIT INEDTSIKE
//