ID   W6TII8_9SPIR            Unreviewed;       143 AA.
AC   W6TII8;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Adenosine 5'-monophosphoramidase {ECO:0000313|EMBL:ETZ18475.1};
GN   ORFNames=BDCR2A_00448 {ECO:0000313|EMBL:ETZ18475.1};
OS   Borrelia duttonii CR2A.
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Borreliaceae;
OC   Borrelia.
OX   NCBI_TaxID=1432657 {ECO:0000313|EMBL:ETZ18475.1, ECO:0000313|Proteomes:UP000019148};
RN   [1] {ECO:0000313|EMBL:ETZ18475.1, ECO:0000313|Proteomes:UP000019148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CR2A {ECO:0000313|EMBL:ETZ18475.1,
RC   ECO:0000313|Proteomes:UP000019148};
RA   Schwan T.G., Raffel S.J., Porcella S.F.;
RT   "Comparative genomics of relapsing fever spirochetes.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETZ18475.1}.
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DR   EMBL; AZIT01000001; ETZ18475.1; -; Genomic_DNA.
DR   AlphaFoldDB; W6TII8; -.
DR   PATRIC; fig|1432657.3.peg.448; -.
DR   Proteomes; UP000019148; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd01277; HINT_subgroup; 1.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   InterPro; IPR039384; HINT.
DR   InterPro; IPR019808; Histidine_triad_CS.
DR   InterPro; IPR001310; Histidine_triad_HIT.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR036265; HIT-like_sf.
DR   PANTHER; PTHR46648:SF1; ADENOSINE 5'-MONOPHOSPHORAMIDASE HNT1; 1.
DR   PANTHER; PTHR46648; HIT FAMILY PROTEIN 1; 1.
DR   Pfam; PF01230; HIT; 1.
DR   PRINTS; PR00332; HISTRIAD.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   PROSITE; PS00892; HIT_1; 1.
DR   PROSITE; PS51084; HIT_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019148}.
FT   DOMAIN          9..118
FT                   /note="HIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51084"
FT   MOTIF           103..107
FT                   /note="Histidine triad motif"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601310-3,
FT                   ECO:0000256|PROSITE-ProRule:PRU00464"
FT   ACT_SITE        105
FT                   /note="Tele-AMP-histidine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601310-1"
SQ   SEQUENCE   143 AA;  16098 MW;  D4C21A07117A8DA3 CRC64;
     MEEILSDCIF CKIVKNEISC YKVYEDNLIL AFLDINPLNI GHTLVIPKQH SNDILDVNDE
     LDGQLLGVCK KVALSLKKLD FNICQGVNIY SAIGSEAGQV IFHTHFHIIP RFQGDNLGFK
     RNCSIELSGD EYLDLSKKIS KNI
//